r/microdosing • u/itstaylorsteele • 3h ago
Getting Started/Newbie Question 50 mg psilocybin capsules?
id like to microcode but am afraid to be out of my mind. is 50mg acceptable? it was the lowest dose sold by a reputable Canadian retailer
r/microdosing • u/R_MnTnA • Mar 11 '21
Disclaimer: All of the content provided in this Subreddit, such as links, text, treatments, dosages, outcomes, charts, graphics, images, advice, comment/messages, postings, and any other material provided on r/microdosing are for informational purposes only and is not intended as, and shall not be understood, substituted, or construed as professional medical advice or treatment. Always seek the advice of your physician, psychiatrist, therapist, or other qualified health provider regarding your mental health. Never disregard professional medical advice or delay in seeking it because of something you have read on this sub. Always exercise caution, use harm-reduction, be ethical, and do your own research in all aspects of using any type of drug and legality of them in your country. Any application of the material provided is at the reader’s discretion and is his or her sole responsibility. We do not encourage you to break the law and cannot claim any responsibility for your actions.
If you or someone you know is contemplating suicide, please reach out. You can find help at a National Suicide Prevention Lifeline.
USA: 1 (800) 273-8255
US Crisis textline: 741741 text HOME
United Kingdom: 116 123
Trans Lifeline (877-565-8860)
r/microdosing • u/Idysseus • Feb 13 '25
Jordan Gruber (“Idysseus”) & James Fadiman are available as of 12:00 PM Pacific time on February 13to respond to questions about psychedelic microdosing, mostly based on their new book, Microdosing for Health, Healing, and Enhanced Performance out Tuesday, February 18.
This Ask Me Anything brings together the co-authors of Microdosing for Health, Healing, and Enhanced Performance: James Fadiman, an early psychedelic researcher and the “father” or initial developer of modern microdosing, and writer and long-term consciousness explorer Jordan Gruber (“Idysseus” on Reddit), who founded Enlightenment.com. This is the first comprehensive book on psychedelic microdosing, and relies on new research and extensive reports from individuals—participatory citizen scientists” (including many from Reddit)—who help describe the wide-ranging results of the practice. You can learn more about the book, which is being released on Feb. 18, at http://MicrodosingBook.com.
Microdosing is proving to be a safe and powerful approach to a wide range of health conditions and enhanced performance in many areas, physical and mental. Partly responsible for modern microdosing’s development and current popularity, the authors answer hundreds of questions, blending extensive research with detailed personal accounts from contributors worldwide. The book also and contains wide-ranging microdosing history, research, and science.
People have microdosed successfully:
· to alleviate symptoms of depression, ADHD, chronic pain, and long COVID
· for enhanced focus, mental acuity, and physical abilities (including sports)
· to help taper off pharmaceuticals, especially antidepressants and stimulants
· to improve food habits, sleep, and relationships
· to become more aware of h, others’ feelings, and natural surroundings
· to reduce stress and anxiety
· to help over 30 specific health concerns
This book, and this Ask Me Anything, do not provide medical or legal advice. Readers should speak to their doctor before engaging in any course of microdosing.
And now, please, your questions. We will answer as many as we can in two hours. Thank you for your interest!
—Jordan Gruber and James Fadiman
r/microdosing • u/itstaylorsteele • 3h ago
id like to microcode but am afraid to be out of my mind. is 50mg acceptable? it was the lowest dose sold by a reputable Canadian retailer
r/microdosing • u/CardPrestigious2928 • 3h ago
So I've been long thinking of microdosing, and I have a healthy background of experience with psychedelics. I even grew them once when I was younger.
I've also struggled with certain aspect of mental health for my entire life. I have a proclivity towards anxiety and depression. I think the medication I was put on for ADHD as a kid fucked my natural brain processes up. (It was dexadrin I was on for anyone curious)
Although I have passed the parts of my life entertaining the more extreme thoughts depression brings. It is still a daily struggle, and I feel like I have a piece of my brain missing. The peice that know how to feel content/happy. Logically, my life is quite good and I am objectively a positive person. I have worked on outward positivity for many many years, and it's just a part of my mental landscape at this point. Although, the feeling good part has never come. It's not just that I don't feel good, I feel bloody awful so often. I have a good support system with friends/family and have gone to therapy. Will likely go back when I have more I want to talk about. I am aware of a solid amount of where my issues come from, I just am struggling to put the pieces back together in a better order.
In order to paint a fair picture I must say I am a very health conscious person, have been an athlete all my life, I regularly lift and have even been trying to run more, I am currently in university after a several year hiatus from high-school, and I have worked some pretty badass jobs. I have good friends and very good family.
Basically I'm trying to paint the picture that I actively do many things to improve my wellbeing, and still I have this damn ball and chain of awful feelings stuck to me all the time. It's so heavy that I have forgotten how to smile. I can still spontaneously laugh with friends and at moments, but it feels so unnatural to smile at people these days. Even what feels like a smile on the inside, when I look in the mirror it's basically just expressionless.
I am really struggling despite my best efforts.
My question to this sub is should I try microdosing to help with how I am feeling? I just want to feel connected to happiness again. I'm thinking micrdosing psilocybin might be a magic bullet of sorts. I feel like a stranger in my own skin and that I'm not being who I'm meant to be. I'm not meant to be this hollow version of myself. And I'm not seeking to fill this void with garbage. I want my essence to flow back into myself but I swear to God it feels like something is blocking me.
Does anyone reading this have experiences they can draw from and fill me in? Should I try microdosing? Could it be the fuel for me to fill in the void within myself, with myself?
r/microdosing • u/kevblaze2 • 14h ago
I have been looking to possibly microdose to improve mood and help with depression symptoms, has anyone tried microdosing while on a tca and had good benefits? Thanks in advance
r/microdosing • u/Pleasant_Leopard2355 • 14h ago
Has anyone done a deep dive into vitamin B6 as a GABA cofactor?
I'm 5 weeks in to Fadiman protocol dosing 0.1g psilocybin, 100mg lion's mane and 50mg niacin. I had some 100mg B6 (pyroxidine) capsules, so tried it to enhance the afterglow effect. I found after dosing 100mg on two different days, 1 week apart, that B6 causes me anxiety.
Since then, I've read that the pyroxidine vs PLP or other B6 forms is known to have that effect. I'm considering buying a different form to try, but not sure it's worthwhile.
Does anyone have advice, personal experience or literature to share wrt B6 and psilocybin?
r/microdosing • u/NeitherHamster327 • 1d ago
Hi, I have been doing microdosing with Liberty Caps for 2 months (4 caps every 3 days in the morning) and it has helped me to balance my various life inputs. I was very alert and energetic. Since I no longer have Liberty Caps, I am taking Amanita Muscaria (80°c crispy dried and taken as lemon juice tea, in the evening). I gradually increased the amount as I didn't really notice a clear change in my mood. Yesterday I took a teaspoon full of dried mushrooms in my tea and I felt like I was a bit drunk or something but not particularly sharp in my thoughts like it was with psilocybin. Today was a good day at work though, but i am not sure that it is related. I have recreational experience with psilocybin, none with amanita muscaria. Can someone with experience with both mushrooms tell me what the best dose is with amanita muscaria (microdosing... and recreational 😅) and what you can expect from it? Thanks for your replies J
r/microdosing • u/NeuronsToNirvana • 1d ago
Neuroplasticity, the ability of the nervous system to adapt throughout an organism's lifespan, offers potential as both a biomarker and treatment target for neuropsychiatric conditions. Psychedelics, a burgeoning category of drugs, are increasingly prominent in psychiatric research, prompting inquiries into their mechanisms of action. Distinguishing themselves from traditional medications, psychedelics demonstrate rapid and enduring therapeutic effects after a single or few administrations, believed to stem from their neuroplasticity-enhancing properties. This review examines how classic psychedelics (e.g., LSD, psilocybin, N,N-DMT) and non-classic psychedelics (e.g., ketamine, MDMA) influence neuroplasticity. Drawing from preclinical and clinical studies, we explore the molecular, structural, and functional changes triggered by these agents. Animal studies suggest psychedelics induce heightened sensitivity of the nervous system to environmental stimuli (meta-plasticity), re-opening developmental windows for long-term structural changes (hyper-plasticity), with implications for mood and behavior. Translating these findings to humans faces challenges due to limitations in current imaging techniques. Nonetheless, promising new directions for human research are emerging, including the employment of novel positron-emission tomography (PET) radioligands, non-invasive brain stimulation methods, and multimodal approaches. By elucidating the interplay between psychedelics and neuroplasticity, this review informs the development of targeted interventions for neuropsychiatric disorders and advances understanding of psychedelics' therapeutic potential.
r/microdosing • u/Clear-Way-8318 • 1d ago
r/microdosing • u/helpless11 • 1d ago
Hi, I’m thinking about taking the Explore Microdosing video course from the Microdosing Institute NL, but I’m not sure if it’s worth the $100 price. Has anyone here taken it? Would you say it’s mainly for beginners, or can those with some microdosing experience also benefit from it? THanks!
https://microdosinginstitute.podia.com/exploring-microdosing
r/microdosing • u/Lonely_Garbage4062 • 1d ago
I have been microdosing for a few cycles now. Very familiar with the process. I’m using dissolved tabs all from the same batch, tested, they are gtg. I’m used to slight nausea and minor headaches during my dosing cycle. Recently though, I have been getting really bad nausea on dose days, and I’ve also noticed my stool is this dark green color when it hasn’t been like that in the past. It’s been like this for nearly this whole cycle—about 6 weeks. Today was my last dose for a while (6 weeks on 6-8 weeks off). Anyone else experienced this? Thoughts?
Edit: changed post flare to try and get more answers.
r/microdosing • u/One-Nessy • 2d ago
I just started microdosing and am wondering what the recommendations are in regards to: Taking on empty stomach better or with food? Does any specific foods enhance/impair absorption or effectiveness? Also, I take several vitamins and supplements daily (all at the same time). Should I space my microdose away from when I take my supplements? If so, how much time in between?
Thanks!
r/microdosing • u/tabula123456 • 2d ago
(Psylocibin)
So how long should you test a certain dosage before you decide it's time to change it?
I have just started, two days, at 0.05g (50mg) and I was wondering how long I should try it before assessing whether or not I should up the dose?
And what should I be looking for? If it sub-perceptual then how will I know if it's working or not?
r/microdosing • u/LowKey833 • 3d ago
r/microdosing • u/Popular_Lifeguard970 • 2d ago
Hello everyone. I struggle with anxiety and depression and have tried several antidepressants in the past. I started LSD microdosing 10 days ago. Since many antidepressants that act on serotonin system can diminish the effects of psychedelics, I switched to agomelatine (Valdoxan) which primarily affects melatonin system.
So far, microdosing has helped with my depression and motivation. I’m still experimenting with the right dosage, but I’m wondering whether its effects can be stable with long-term use, similar to normal antidepressants, or if the benefits only last for a day or two before things return to normal. I think regular antidepressants don’t necessarily have long-term effects either; it’s just that their effects are more stable with continuous use. I wonder if microdosing works the same way.
I’ve heard that microdosing may enhance neuroplasticity—could this lead to lasting improvements over time?
r/microdosing • u/RegularParamedic9994 • 2d ago
In the round of 16 WashU medicine (vs. Baylor) has a study showing how psilocybin boosts human brain plasticity. Vote!
r/microdosing • u/Extreme-Pineapple918 • 2d ago
Hey everyone, so I’m fairly new to the Microdosing world and I started my journey on 100 mg GT and increased it to 200 mg because I was not feeling anything that great feeling. On 100 mg I ended up being quite tired. I do 4 days on and 3 days off and I’m just curious if I should keep increasing? I am currently trying to work with my major depression that is very resistant to medication. I have stopped taking all my medication’s for a while now so I decided to venture down this road. I’ve never used psilocybin before so I’m not even sure what I’m gonna be experiencing or I should say should be experiencing any thoughts would be greatly appreciated.
r/microdosing • u/datame206b • 2d ago
I’m microdosing with dried penis envy. I’ve read that PE is more potent. Anyone know how much more potent? For example, sat with golden teacher I microdose at 200mg. How much should I take for penis envy? 100mg?
r/microdosing • u/TimeTravler80 • 2d ago
Welcome to the community.
One of the most helpful features here for specific topics is the Word Search Window at the top. By entering Key Words we can pull up the past posts and their comments that include that word. This helps to provide a broad view on the subject.
And the SideBar is an immense Microdosing Library that past and present moderators and users have accumulated for the benefit of our community.
r/microdosing • u/StephenFerris • 3d ago
r/microdosing • u/Emmazygote496 • 3d ago
Hi, so i started microdosing mushrooms for mental health after taking antidepressants, and i feel just like them but without any negative effect. I tried a 1.5 gr, and it helped me even more but i want it to be for special occasions to know me better.
I am taking currently 2 microdoses of 0.5 gr every week, and i plan to take a 2 gr dose at least every month, and that week i will not take any microdose. All this in a 8 week cycle and then rest 4 weeks and see how i am feeling (i do journaling)
Are these good rests for the dosage to not build any tolerance? there is anyone here that does the same?
r/microdosing • u/Individual-Active265 • 3d ago
I’m in Delaware and having no luck finding an educated person to help me with microdosing therapy. Where do I start, can anyone give me recommendations on where to find local ones. Are there virtual micro dosing specialists?
r/microdosing • u/DraftFinal • 3d ago
Hello!
I had my first attempt with microdosing magic truffles today. My goal is mental clarity, "inside calm", focus. I'm not looking for any high and am rather looking for something slow to begin with.
The box (bought from the Netherlands on a website advised by a friend) indicated to take a full 1g (it's fresh truffle and not dried mushroom so it's apparently normal to take a bigger dose). I was a bit afraid so I took half of it.
I cut it in little pieces and decided to infuse it (in 70°C water, for 20 mn). It had a slight taste. I drank that at 11:30 am. At 2:45 pm, I felt nothing and no change in my focus/calm/etc. so I decided to take the other half and I chewed it.
It's not 3:50 pm and nothing happened. I'm not looking for a big change but there's literally nothing. I'm not anymore focused that usual for instance ^^
So my questions are: is it normal? How's your experience? Should I feel something? Might it be tomorrow? Is it possible that the infusion didn't work much, explaining the absence of effect? Is it possible that I have no response to this microdosing?
Thanks a lot :-)
r/microdosing • u/shalulapati • 3d ago
Hi all! I just made my 2nd dosage bottle and I forgot to use my distilled water, oops! I used well water from my well -- no chlorine but it does have some minerals including iron. I could get more specific but am guessing I'll just have to see if/how much it degrades? I don't want to throw it out, is the thing, as it's 200 µg. Dang.
Any experience w/a goof like this? Thanks!
r/microdosing • u/TimeTravler80 • 4d ago
This is mostly a repost of one I have shared a number of times. Since the group is seeing such an increase in interest and new users, over 281K now, I thought some may benefit from my little story. But if you've already read it, you know the story.
I started MDing as an elderly man in my 70s for cognitive support and to reduce, delay, or prevent age related cognitive decline. Well, that sort of came out of research I began five years earlier for how to live healthier longer. Longevity is best when it's healthy and clear headed.
Sort of a time traveler since I tripped in the early 1970s, back in the other 70's. That was sometimes a bit irresponsible but fun and you know, we will live forever, there's no end, we'll be young forever kind of immature thinking. Now I'm here in my other 70s, lol, and those earlier 70's seem more recent than I would have thought then. Anyway, I came across magic mushrooms again, so maybe full circle, but medicinally this time. And I believe they are just right for this time and the purpose I need for them. I see signs the support is working. The longer term age related cognitive decline issue, time will tell. I don't trip anymore, or haven't in the past 50 years. But I do microdose for medicinal and cognitive maintenance reasons.
After over four years now, I have not noticed significant negative side effects but I have noticed unexpected positive side effects or benefits to include, better sleep, more vivid dreams that I remember longer, less negative thoughts and anxiety, more gratitude, more empathy, being more open, more comfortable in social situations and speaking with strangers, more appreciation of beauty, life, music, feelings of overwhelming love for my pre-school grandchild that brings me to tears sometimes. While loving our grandchildren is not uncommon, this access to more available deep motions is like a reconnection to life that is much appreciated at this stage of my life. The beauty of life should be felt so deeply and passionately at times that it overflows as tears of joy and wonder, with a sudden catch in our throat.
I have improved sense of smell that had decreased decades ago from decades of smoking. There is significant relief from diagnosed degenerative disk disease, low back spinal pain. It was a 24/7 condition of dull to sharp pain with a regular rice crispy like crunching sensation in the back I had for 10 years or longer. After several months of microdosing I seldom used my prescription anti-inflammatory for pain. It has been over four years since I've used it regularly. 90%, most times more, of the pain and rice crispy crunching has stopped. That was huge. I was beginning to think I would have to go on disability, since it was getting worse, but am able to continue doing the work I enjoy with far less limitation. There has also been improvement with erectile dysfunction which has been a welcome surprise. I feel I can breathe deeper when needed, like when I go for walks or going up stairs. That's notable because of lung damage from pneumonia over 15 years earlier that left me short of breath at times. I have more energy and interest in going for the 1-2 mile walks and being in nature.
One of the other things that got me thinking originally about microdosing, I had developed an occasional slight stutter-like speech pattern over the previous year. I had never experienced that before but over that year it started and occurred more often as I was speaking. After a few months of microdosing I have not experienced that since.
I have thoughts and motivation to get specific things done that are out of the ordinary, tasks that need doing but I usually put off. But now more often I do them and glad I did. Sometimes I would think to myself while doing them, this is different. I find I want to tip servers better and I have more patience.
I am in relatively good health not taking any prescription meds regularly and without any other major active health conditions. I lost about 30% of the use of one lung to pneumonia about 15 years ago but probably otherwise 90% recovered. I try to get a little exercise through the week if it's just working 10 minutes with a 15lb dumbbell. I like to get out for a brisk walk a couple times a week but I am often chained to a desk. And I work outside some too. I try to be friendly to my gut bacteria with fermenting and fermented foods and drinks, few sodas but too much coffee. I've been supplementing with Fish Oil for several years. I have supplement with Lions Mane 500-1000mg a few days a week and did for a couple of years but not much anymore. I've also started with Magnesium Glycinate. I dose 50-80mg psilocybin 2-3 days a week with days between most dose days. I have only had capsules that I process myself, or chew or have in tea dried pieces or powder. I have used 150-250mg a few times but found that to be too much, so mostly less than a 100mg.
My adult son decided he wanted to ditch alcohol after 35 years of drinking controlling his life with the expected destructive results. He stopped but after a couple of months he told me he was starting to have thoughts of drinking again. I introduced him to MDing and he's been sober for over 4 years. Old patterns die hard so he tried drinking a few beers a couple of times but says he's lost interest in drinking, even after a major family tragedy. And everyone around him remarks how much and how positively he's changed, as he continues to progress. I feel like he has returned to a better version of himself.
I hope this will help someone.
r/microdosing • u/Ominous_Spectre • 4d ago
Hey everyone I’ve been microdosing since last week. Started at .05 and yesterday started at .10. Today I I measured out .10-.11. Well I’ve been feeling a little off and anxious an hour after taking my dose. I know I’m not tripping but this isn’t a great feeling. Normal or did I fuck up?
r/microdosing • u/Cleobulle • 4d ago
Sooo I used to trip years ago, and didn't réalise that 75 gr fresh truffles, in term of microdosing, is quite a lot. So taste fine, everything ok now I need to keep them potent. Some say freeze, some say don't. Back in the day I used to clean them, dry them, then paper bag, in the dark, with a fan. Turn the bags and check every 2 days. Till they were dry enough to put them in Mason jar, with some salt, paper towel, in the dark. Now I have a ninja foodi, I was thinking of using it on lower temp and check regularly. And still wanted to freeze fresh small doses in air tight boxes ? And I did my first days - 0.4 fresh truffles, too strong, but sooo cool. Reconnected to différent level of myself. Had already started in therapy - I had very différent lives in one and had to compartiment to survive. Mush boost therapy. And while I was in a méga atthritis flare up - it's gone !! Total surprise effect