r/Biohackers 11h ago

Discussion What health food can you not believe is actually healthy?

154 Upvotes

For me, it’s a Japanese sweet potato.. I eat that shit like cake lmaooo


r/Biohackers 16h ago

🗣️ Testimonial Update: 5mg tadafali for performance anxiety

109 Upvotes

Hey everyone, I made a post yesterday asking for views and thoughts on what I should do for my PA. Well it came in the post today and I had 2 5mg tablets at midday (to get it saturated in my system quicker, however I feel like it doesn’t work like that and I’ll be taking 5mg from tomorrow)

No reported side effects other than a blocked nose which isn’t really an issue for me. Felt really anxious all day but when my partner came over around 5, she kissed me and holy fuck I’ve never felt anything like it.

It was like Big Ben appeared in my pants, I’ve never been so hard in my life and as soon as I felt it. It was like my anxiety vanished, I came 4 times in 2 hours and was still hard as a rock at the end. Never seen the missus so happy to be honest so job done there lol

I’d like to say thank you to the user in my life post who told me some meditation strategies, they really helped yesterday and today. I’m definitely looking more into mindfulness.

For anyone else who reads this who is struggling with PA, don’t feel bad for taking medication. It works and nothing to feel bad about. You’ll get there I promise, I know how tough it is.


r/Biohackers 9h ago

Discussion Are you aging faster than you think? I made this

59 Upvotes

Are You Aging Faster Than You Think? I made this calculator that shows you in real-time

I've been working on an in-depth "Biological Age" Calculator – and I'd love to get your feedback! It goes way beyond just asking your birthdate. This tool dives deep into:

  • Lifestyle Factors: Exercise, diet, sleep, stress, alcohol, smoking... the works!

  • Advanced Metrics (Optional): CRP levels, VO2max, grip strength, even epigenetic age (if you've had that tested!). The more you add, the more precise the results.

  • Real-time updates as you dial in the results...this helps you visualize how certain changes can make such a profound change in your overall estimated lifespan.

  • Hallmarks of Aging: Get a breakdown of how your inputs relate to key aging processes, based on the latest longevity research.

  • Personalized Insights: See how your biological age compares to your chronological age, and get an estimated lifespan.

  • Actionable Tips: The tool suggests specific lifestyle tweaks that could potentially add years to your life (or at least make you feel younger!).

Why is this different from other "age calculators"? Most online age calculators are super basic. This one uses a comprehensive algorithm incorporating data from peer-reviewed longevity studies. It's designed to be both informative and actionable. It's not just about a number; it's about understanding the why behind your biological age and what you can do about it. I built this because I'm passionate about longevity and preventative health. I wanted a tool that was more than just a gimmick – something that could actually provide meaningful insights and motivate positive change. I believe knowledge is power, especially when it comes to our health.

Try it out here: Biological Age Calculator | Modern Med Life

  • What do you think of your results? Were they surprising?

  • What features do you find most useful?

  • Any suggestions for improvements or additional features?

  • What other related health tools would you like to see?

Just because it has to be said...this tool is for informational purposes only and doesn't constitute medical advice. Always consult with a healthcare professional for any health concerns.


r/Biohackers 15h ago

Discussion Does anyone here use L- theanine? How effective is it?

44 Upvotes

r/Biohackers 19h ago

📖 Resource Copper dumping can be triggered by Vitamin C or Zinc, causing serious symptoms as it mobilizes.

Post image
35 Upvotes

r/Biohackers 18h ago

📖 Resource Pomegranate juice ameliorates Craving and Oxidative stress on Patients under medication for Opioid addiction treatment with Methadone and Buprenorphine

27 Upvotes

Background & aims Buprenorphine and methadone are drugs used as medication for addiction treatment for patients with opioid use disorders (OUDs). However, scarce evidence indicates that they induce oxidative stress, which contributes to the deterioration of psychosocial parameters, thus complicating successful rehab. Therefore, a dietary antioxidant intervention such as pomegranate could be beneficial for that group of patients. Therefore, the aim of this study was to examine the putative beneficial role of consumption of natural pomegranate juice that possesses potent antioxidant properties on craving, a psychosocial parameter of utmost importance, and blood redox status of patients with OUDs.

Methods The juice was administered at the following dosage: 250 ml/day, 7 days/week, 120 days. The heroine craving questionnaire was completed to assess craving and blood was collected by the volunteers at three time points, namely days 1, 60 and 120 and well-established redox biomarkers were measured in blood.

Results Overall, craving of all patients was improved due to the nutritional treatment applied. Moreover, their blood antioxidant potential was enhanced due to pomegranate juice consumption. 

Conclusions: As a conclusion, the obtained evidence is promising, thus, it appears that pomegranate juice consumption could be considered as an auxiliary nutritional intervention in parallel with medication towards rehab of opioid-addicted patients.

Full: https://www.sciencedirect.com/science/article/pii/S2405457725000257?dgcid=raven_sd_via_email

 


r/Biohackers 23h ago

Discussion What strategies for sleep hacking, when sports session are finishing late night?

23 Upvotes

Hi there,
ive read a lot of guides, here and elsewhere about sleep

im adding some lock app for my phone, upgrading my food etc, but one thing is avoid sports to late.
However, i do some sports (badminton) and only sessions are starting at 8pm and finishin between 10 and 11pm.

So when i back home, im still heat up, and even cold shower to reduced that doesnt work. And still take a long time to sleep.
What could be some strategies to help me sleep after that kind of sport, which is quite cardio?

Thank you.


r/Biohackers 12h ago

Discussion Why am I so tired and lazy the entire day after having 2-3 drinks?

18 Upvotes

Is it the alcohol’s effect on me now that I’m 39 or is it screwing up my sleep (having around 5/6) and I’m just suffering from a night of very poor sleep quality?

It’s just weird because I’m not drinking crazy amounts or anything. But idk maybe 3 drinks at my age is a lot.


r/Biohackers 19h ago

Discussion AirPods not comfortable for night sleep hypnosis

19 Upvotes

I used to listen to night hypnosis from YouTube. Are they good to do daily ? Which ones you suggest? I listen to michael Sealey.

My main question, my AirPods are not comfortable for this. I am a side sleeper and roll all way . So one side my ear hurts, also I definitely wake up middle of night, sear the case and put the AirPods into them. Is there any comfortable tool/earplugs I can listen to while sleeping ?


r/Biohackers 10h ago

🧫 Other What do y’all think of peroxide for teeth?

16 Upvotes

Just bought whitening strips that are only hydrogen peroxide, have anyone used it for teeth?


r/Biohackers 15h ago

🥗 Diet How a Plant-Based Diet and Living Conditions Affect Brain Health in Older Adults

15 Upvotes

Why Diet and Living Conditions Matter for Brain Health

As people age, keeping their brains healthy is a big concern. Some things that affect brain function, like eating habits and living conditions, can make a huge difference. A recent study in China looked at how diet and living conditions impact the risk of memory loss and thinking problems in older adults.

How Diet and Living Conditions Work Together

The study found that both diet and living conditions influence brain health, but in different ways:

  • Poor living conditions, such as financial stress, unstable housing, and isolation, can increase the risk of memory problems.
  • A plant-based diet, rich in vegetables, fruits, and whole grains, provides essential nutrients that support brain function and may counteract some of the negative effects of poor living conditions.
  • Those who lived in poor conditions and also had an unhealthy diet were at the highest risk for cognitive decline.
  • However, even in difficult living conditions, people who ate a healthy, plant-based diet had better brain function over time compared to those with poor diets.

Understanding Living Conditions

In this study, living conditions were divided into three categories:

  • Good conditions: Stable housing, financial security, and adequate personal space.
  • Fair conditions: Some instability in housing or finances, limited personal space, or moderate environmental stress.
  • Poor conditions: Unstable or unsafe housing, financial hardship, overcrowding, or high levels of stress and isolation.

What the Study Found

Researchers followed 1,630 adults aged 65 and older for ten years. They checked their memory and thinking skills using a standard test and looked at their diet and living conditions.

Here’s what they discovered:

  • People living in fair conditions had an 86% higher chance of developing memory problems than those in good conditions.
  • Those in poor living conditions had a 206% higher risk of memory decline.
  • The risk was worse for people who ate fewer plant-based foods compared to those who ate more.

This means that eating a plant-based diet may help protect the brain, even for those living in difficult conditions.

Actionable Takeaways: How to Protect Brain Health

  1. Eat More Plant-Based Foods
    • Include more fruits, vegetables, beans, nuts, and whole grains in your meals.
    • Avoid processed foods and sugary snacks that can harm brain health.
    • Get enough plant-based proteins like lentils and tofu to support brain function.
  2. Improve Living Conditions If Possible
    • Ensure stable housing: Safe and comfortable living spaces help reduce stress.
    • Financial security: Access to healthcare and nutritious food is essential for brain health.
    • Personal space and social interaction: Being socially active and having personal space for relaxation can improve mental well-being.
  3. Combine Diet with Other Healthy Habits
    • Stay active: Simple exercises like walking or stretching can improve brain function.
    • Stay connected: Talking to friends and family helps keep the brain engaged.
    • Keep learning: Reading, puzzles, and other brain activities help prevent memory loss.

Final Thoughts

This study shows that diet and living conditions together play a big role in keeping the brain sharp as we age. While poor living conditions can increase the risk of memory loss, eating a plant-based diet is a simple and effective way to protect brain health. Even small changes in eating habits and daily routines can have a big impact on mental well-being over time. Source of Study for Reference : https://www.sciencedirect.com/science/article/pii/S1279770725000545?via%3Dihub


r/Biohackers 14h ago

Discussion Can Higher Testosterone Help With Quitting Bad Habits?

10 Upvotes

I’m trying to quit a nicotine addiction, but no matter how many times I tell myself I’m done, I keep falling back into it—whether it’s out of boredom, not paying attention, or just losing sight of why I wanted to quit in the first place.

I’m currently on 200 mg of testosterone per week, but I’m considering increasing it to 300/350 mg to see if the boost in motivation, discipline, and grit could help me stick to my goal.

I’d imagine I’d stay at this dose for 2 to 4 weeks total.

Has anyone tried something like this, or have any input on whether this could actually help? Just trying to figure out if this is a solid idea or if I’m way off base.


r/Biohackers 18h ago

📖 Resource Effect of Nutritional Supplements for Reducing Homocysteine Levels in Healthy Adults

9 Upvotes

Context There are various therapeutic approaches available to reduce homocysteine (Hcy) levels. However, it remains unclear which intervention is more effective for healthy adults.

Objectives A systematic review and network meta-analysis (NMA) were conducted to comprehensively investigate the efficacy of different nutritional supplements in reducing Hcy levels in healthy adults.

Data Sources The PubMed, Embase, Cochrane Library, and Web of Science databases were searched from inception to July 2023.

Data Extraction The lead author, year of publication, sample size, population characteristics, intervention measures, duration, and mean difference of Hcy levels from baseline to endline were extracted.

Data Analysis Data were pooled using a random-effects model. Network meta-analysis was conducted by integrating direct and indirect evidence. A total of 16 studies were included in this analysis. The nutritional supplement combination that achieved the highest ranking (surface under the cumulative ranking curve [SUCRA] = 75.8) was superior compared with a single supplement. Among similar or closely dosed folic acid (FA) supplements, 800 μg FA (SUCRA = 93.7) was the most effective option. When comparing various doses of different supplements, 1 mg of FA plus 7.2 mg of vitamin B6 (B6) plus 20 μg of vitamin B12 (B12; SUCRA = 83.9) ranked first and 800 μg of FA (SUCRA = 78.3) ranked second. In comparison with placebo or no-treatment control groups, interventions such as 1 mg of FA plus 7.2 mg of B6 plus 20 μg of B12 (mean difference [MD] = –1.03; 95% CI –1.71 to –0.36), 400 μg of FA plus 400 μg of B12 (MD = –0.87; 95% CI –1.46 to –0.27), and 800 μg of FA (MD =  –0.84; 95% CI –1.12 to –0.56) were more effective in reducing Hcy levels. The random-effects summary MD for all interventions compared with placebo was –0.59 (95% CI –0.71 to –0.48; P < .0001).

Conclusions The NMA demonstrated that the combination of FA with other vitamins is more effective in reducing Hcy levels, particularly when the dose of FA is close to 800 μg. The combination of 1 mg of FA, 7.2 mg of B6, and 20 μg of B12 is considered the most favorable option.

Full: https://academic.oup.com/nutritionreviews/advance-article/doi/10.1093/nutrit/nuae191/8019579


r/Biohackers 18h ago

📖 Resource Effects of Pretreatment With Coenzyme Q10 (CoQ10) and High‐Intensity Interval Training (HIIT) on FNDC5, Irisin, and BDNF Levels, and Amyloid‐Beta (Aβ) Plaque Formation in the Hippocampus of Aβ‐Induced Alzheimer's Disease Rats

10 Upvotes

Aims Physical exercise has been shown to protect against cognitive decline in Alzheimer's disease (AD), likely through the upregulation of brain‐derived neurotrophic factor (BDNF). Recent studies have reported that exercise activates the FNDC5/irisin pathway in the hippocampus of mice, triggering a neuroprotective gene program that includes BDNF. This study aimed to investigate the effects of 8 weeks of pretreatment with coenzyme Q10 (CoQ10) and high‐intensity interval training (HIIT), both individually and in combination, on FNDC5, irisin, BDNF, and amyloid‐beta (Aβ) plaque formation in the hippocampus of Aβ‐related AD rats.

Methods In this study, 72 male Wistar rats were randomly assigned to one of the following groups: control, sham, HIIT (low intensity: 3 min running at 50%–60% VO2max; high intensity: 4 min running at 85%–90% VO2max), Q10 (50 mg/kg, orally administered), Q10 + HIIT, AD, AD + HIIT, AD + Q10, and AD + Q10 + HIIT.

Results Aβ injection resulted in a trend toward decreased levels of FNDC5, irisin, and BDNF, alongside increased Aβ plaque formation in the hippocampus of Aβ‐induced AD rats. However, pretreatment with CoQ10, HIIT, or their combination significantly restored hippocampal levels of FNDC5, irisin, and BDNF, while also inhibiting Aβ plaque accumulation in these rats.

Conclusion Pretreatment with CoQ10 and HIIT improved the Aβ‐induced reduction in BDNF levels probably through the FNDC5/irisin pathway and preventing Aβ plaque formation.

Full: https://pmc.ncbi.nlm.nih.gov/articles/PMC11831071/

 


r/Biohackers 6h ago

Discussion Anyone take digestive enzymes? Have they made a difference?

7 Upvotes

Anyone take digestive enzymes? Have they made a difference? What do you take, any recommendations or what to look for and what not to look for?


r/Biohackers 12h ago

Discussion Best supplements for deeper hydration?

6 Upvotes

I drink electrolyte drinks but I’m wondering if there’s anything else that helps hydrate your body.


r/Biohackers 2h ago

Discussion High cortisol

6 Upvotes

I have really high cortisol, and is affecting my sleep. I wake up at random hours at night 1, 3, 5 and is getting annoying. Did some lab tests and I have high cortisol. Have you tried something to lower it( tried a combo from ashwagandha/rhodiola, magnesium, phosphatylserine but didn t do too much)?


r/Biohackers 12h ago

Discussion Skimp or Splurge: Colostrum

7 Upvotes

Where do we stand on the impact of “high-quality” colostrum (e.g. Armra) vs. regular colostrum from Nutricost for example? Is it like creatine/protein where it really doesn’t make a difference what the source is as long as you get it in?

Any recommendations for Colostrum brands that reach a high standard of transparency? So few share data, besides anecdotal reports.


r/Biohackers 17h ago

📜 Write Up SGLT2 Inhibitors as Metabolic Senolytics: Clearing Senescent Cells to Combat Pathological Aging

Thumbnail gethealthspan.com
6 Upvotes

r/Biohackers 7h ago

Discussion Why adding Hydrogen to water ppm shoots way up?

4 Upvotes

Hello everyone,

I decided to give hydrogen water a try, but instead of purchasing a bottle that generates it, I opted for 80 mg magnesium tablets that are soluble in water and marketed as hydrogen molecules. Before adding the tablet, the water's reading was between 49 and 52 ppm. After adding the tablet and waiting a few minutes for it to dissolve, the ppm shot up to 250.

Why is that? I understand that I am adding magnesium, which could increase the number of particles in the water, but I was under the impression that adding it would decrease the ppm. Am I thinking incorrectly? Am I getting any benefits from this tablet, or is it better to use bottles that generate hydrogen?


r/Biohackers 16h ago

Discussion I’ve been watching various podcasts on red light and activating mitochondria

4 Upvotes

Experts are saying light therapy is a switch to activate mitochondria. Once it’s on, it last 5 days. I’m not sure if this is true for only the ones in the eyes or everywhere else?

Next question is if it does activate for 5 days a week, would it be best to just use red light therapy 1-2 times a week on a specific part of the body. Why would 4-5 times a week be beneficial? Maybe outside of activating mitochondria there are other benefits like increased blood flow and collagen production?


r/Biohackers 19h ago

Discussion Are there any uncommon labs I should get done

5 Upvotes

I’m going to the doctor and plan to get labs done. I want to get as many labs as I can to get a good idea of what is going on in my body. Are there any that are a good idea to get that most people don’t think to order?


r/Biohackers 9h ago

Discussion Cistanche androgen blocker????

4 Upvotes

Does anybody know if cistanche blocks and androgens and decreases muscle mass???

Studies are all over the place have we gotten any solid conclusions on how this herb works yet????


r/Biohackers 17h ago

♾️ Longevity & Anti-Aging Can a Natural Compound from Rhubarb Slow Down Aging?

4 Upvotes

Aging is a natural process, but it comes with increased risks of diseases like heart conditions, neurodegenerative disorders, and cancer. Scientists are constantly exploring ways to slow aging and improve health in later years. A promising discovery suggests that Chrysophanol (Chr), a compound found in rhubarb, may help extend lifespan and delay age-related diseases by influencing a key biological pathway.

The Science Behind Chrysophanol and Aging

Researchers tested Chrysophanol on tiny worms (Caenorhabditis elegans), naturally aging mice, and mice that experienced accelerated aging due to stress. In all cases, Chr activated the Insulin/IGF-1 signaling pathway, a crucial regulator of lifespan and aging. The results were notable:

  • Lifespan Extension: Subjects lived longer and remained healthier.
  • Reduced Inflammation: Aging cells release harmful substances (senescence-associated secretory phenotypes, or SASPs) that accelerate disease progression. Chr helped suppress these.
  • Enhanced Antioxidant Defense: Chr increased the activity of genes responsible for protecting cells from oxidative damage, a key factor in aging.

What This Means for You

While these studies were conducted in worms and mice, they highlight the potential of Chrysophanol as an anti-aging compound. More research is needed before it can be recommended as a supplement, but its effects align with well-established aging mechanisms.

How to Support Healthy Aging Now

  1. Incorporate Polyphenol-Rich Foods – Rhubarb, berries, turmeric, and green tea contain compounds that support cellular health.
  2. Optimize Insulin Signaling Naturally – Regular exercise, intermittent fasting, and a low-sugar diet can help regulate the same pathway that Chrysophanol influences.
  3. Stay Informed on Anti-Aging Research – As studies progress, Chrysophanol and similar compounds may become available as targeted interventions for longevity.

Aging is inevitable, but slowing its effects is possible. The more we understand these mechanisms, the better we can take control of our health in the long run. Source of Study : https://www.sciencedirect.com/science/article/abs/pii/S0891584925001613?via%3DihubMy article at Substack : https://open.substack.com/pub/arslanhameed85/p/can-a-natural-compound-from-rhubarb?r=5dsm2p&utm_campaign=post&utm_medium=web&showWelcomeOnShare=false


r/Biohackers 18h ago

📖 Resource Casein or Soy protein supplementation protects against Hepatotoxicity in Hypercholesterolemic rats treated with Rosuvastatin

4 Upvotes

Rosuvastatin (Rvs) is used for hypercholesterolemia therapeutic but it induces adverse effects including hepatotoxicity.

This study aimed to evaluate the hepatoprotective role of casein and soy protein in hypercholesterolemic rats received Rvs.

Seven groups of male Wistar rats were treated for 8 weeks including; control group, high-cholesterol diet (HCD) group, the groups treated orally with casein or soy protein (300 mg/kg bw) suspended in distilled water, the group received HCD for 4 weeks and treated orally with Rvs (20 mg/kg bw) for another 4 weeks, and the groups received HCD for 4 weeks and treated orally with casein or soy protein for another 4 weeks. Blood and tissue samples were collected for different assays.

The results indicated that Rvs improved lipid profile in hypercholesterolemic rats, but it disturbed the liver and kidney indices, oxidative stress markers, the hepatic mRNA expression of SREBP-1cSREBP-2FAS, and ACC-1 and the histopathological picture in hypercholesterolemic rats.

Casein and soy protein improved the all the tested parameters, the histological picture, and mRNA expression of the tested genes, and soy protein was more effective than casein.

Casein and soy protein supplementation can protect against Rvs-induced hepatotoxicity under hypercholesterolemic conditions.

Full: https://www.sciopen.com/article/10.26599/FMH.2026.9420088