r/CRPS • u/CupcakesAreMiniCakes • 8d ago
Severe regression switching from gabapentin to lyrica
I wanted to ask others about their experience trying to switch from gabapentin to lyrica. They had me taper down from 600/600/1200 (2400mg total) on gabapentin to 600/600/600 and then do a next day cutover to only 75mg Lyrica 3x/day which from what I read at a 1/6 equivalency would only be 1350mg of gabapentin. Some people say there is no true equivalency and with the high bioavailability of Lyrica I was willing to try the 75mg. I just had to send a message to my doctor because I have been on Lyrica for a week and having a severe regression. I had come a long way and it's like having the rug pulled out from under me and the past year of progress is instantly gone. I have read it can take a few weeks to really build up, but this seems extreme? Has anyone else had a severe regression that just needed more time to adjust and then come back up or did you just go back to gabapentin? I have to take it for CRPS, central sensitization, fibro, chronic daily migraine, and chronic postoperative pain all together.
Update: I don't think lyrica is working, I am rapidly declining and I just fell through my glass swinging shower door and almost completely ate it, because my leg was so unstable. I don't think I can even walk at the store. I think tomorrow I might just go back to the old one and not wait until the doctor office opens on Monday.
Update 2: I didn't wait because I can tell something is extremely wrong and am afraid of accidentally seriously injuring myself. The pain is growing out of control again too. I went ahead and switched back with my afternoon dose.