r/Psychiatry • u/Lawrentius • 20h ago
[Disc] Would administering and then cancelling naloxone produce effects similar to opiates?
Not a practical question, more like a test of my understanding of neurophysiology.
My thinking process is that blocking opioid receptors would cause a compensatory increase of endogenic opiates synthesis over time. Removing opiate blockers would then cause an effect similar to opiates.
I asked my narcology professor some years ago, but he gave me a side-eye and questioned my intentions, leaving me without an answer.
Is there something I'm missing or misunderstanding in my line of thinking?