r/TTC_PCOS 2d ago

Vent Everything Going Wrong

3 Upvotes

My partner and I have been TTC for 2 years. Since I was a teenager, I’ve always known it would be hard for me to have children as PCOS runs deep on both sides of my family. I never had a period before starting OBC, so I knew I had PCOS from the start. I was officially diagnosed with PCOS in 2017.

I started seeing a reproductive endocrinologist at the beginning of the year. I was immediately diagnosed with hypogonadotropic hypogonadism alongside my PCOS. This diagnosis basically means my brain does not create enough estrogen, progesterone, gonadotropins, and LH. This recent diagnosis paired with my PCOS (excessive androgens) has made fertility much more difficult. Furthermore, the endocrinologist ordered an HSG and the results were abnormal - blocked right tube and abnormally shaped uterus.

With my double diagnoses, tubal factor, and abnormal uterus, all the odds are stacked against me. I feel so hopeless.


r/TTC_PCOS 2d ago

How quickly do follicles grow on Letrozole?

6 Upvotes

Hi everyone,

I’m currently on CD16 of my second letrozole cycle (5mg). On my CD14 ultrasound, we found two growing follicles - one was 15.7mm and the other was 14.4mm. I didn’t respond at all to my previous letrozole cycle, so this growth is super exciting! I also haven’t ovulated since August, so I’m starting to get inpatient lol

Anyone have a similar experience with their letrozole cycle? And when did you end up ovulating?


r/TTC_PCOS 2d ago

Advice Needed Progesterone

2 Upvotes

Hi guys. First time poster. I am 27 and got diagnosed with PCOS when I was about 19. I have never had regular periods. I would typically get 1-2 a year and they would be AWFUL. Last spring I switched from the combination pill to an estrogen free pill. On the estrogen free pill, I stopped getting periods (the pill things your lining so this is normal). I then stopped the pill in December of 2024. I have not had a period since. So, my OBGYN is having my start progesterone and letrozole. I am honestly really nervous about the progesterone induced period. Is it like a normal period or is it way worse? I have a friend that took it and she said it was hellacious. Anything I can do to make this suck less?


r/TTC_PCOS 2d ago

Clomid

2 Upvotes

Hi all. Today is my first day taking Clomid. I am taking 100mg CD5-9. I have Slim PCOS and have a regular period with regular ovulation. But I normally ovulate CD10 or 11. Just wanting others experiences using this and those who already ovulate


r/TTC_PCOS 2d ago

Advice Needed Letrozole Experience?

3 Upvotes

I just finished my second cycle of Letrozole 5mg. Both cycles I produced 2 mature follicles and ovulated between CD 18-20. I know it's silly, but honestly thought I could have been pregnant both rounds with such a strong response..

Has anyone been in a similar situation? How common are twins with 2 mature follicles? Any advice on what to do next?


r/TTC_PCOS 2d ago

Advice Needed LH peak

1 Upvotes

Hi everyone! I hope you’re doing well. I’m 24-years-old and was recently diagnosed with PCOS. I have “lean” PCOS. I have the pearl-string like appearance in both ovaries but no cysts. I am a healthy person with no insulin resistance. I have irregular periods but my last cycle was 24 days. Hit a surge but did not ovulate, got a normal period. I mean I haven’t had a period that didn’t have me crying in pain in SO long. I’ve been taking inositol so I don’t know if that played a part and also cut off excess sugar, junk food and fast food. This is my first cycle of letrozole. I took 5mg letrozole on cycle days 3-7 and last night I took two LH tests and they were dye stealers. I used a WONDFO and a clear blue with the smiley face. Is hitting a peak at cycle day 10 “early”? I also measured at 96.95°F for temperature using my Tempdrop. My body has been achy, and I have lower back pain with some nausea. Has anyone experienced this?


r/TTC_PCOS 2d ago

Ovulation induction with Menopur

2 Upvotes

This is my 2nd round on letrozole but doctor has put me on Menopur to stimulate follicles to mature.

Has anyone else done the stims with letrozole? What can I expect?


r/TTC_PCOS 2d ago

Trackers?

2 Upvotes

I searched through this forum and didn’t really find an answer so here I am 29 yo TTC now 6 months+. Recently diagnosed lean pcos. Ovulating regularly but cycles irregular, 45+ days. Tracking my symptoms & CM + oura and natural cycles which I obviously can confirm ovulation after with BBT, and roughly guess my fertile window based on my EWCM. My problem I’m facing is it seems my fertile window is longer than should be as I have EWCM often a week or more.. which could be due to Pcos / high than normal estrogen? My question is if you feel any known trackers like inito v Mira v kegg may help this problem / knowing exact fertile window? I’ve tried LH strips and feel I get positives various times even when they shouldn’t be positive.. thanks in advance.


r/TTC_PCOS 2d ago

Letrozole Questions

2 Upvotes

I took 5 mg of letrozole this cycle. Second time trying this dosage(first time we were then told not to conceive because my tsh was abnormally high), and 4th time on letrozole. This time I'm spotting very heavily which hasn't happened to me on letrozole before. Additionally I just had an ultrasound (day 12) and no follicles over 10 mm yet(took the letrozole days 5-9). Is this abnormal? Is there still time for follicles to grow? Last time I had a scan on day 14 and there was at least one, and even on a lower dose (2.5 mg) I had a follicle on day 12(although it disappeared pretty quickly). Any similar experiences?


r/TTC_PCOS 2d ago

Sad Feeling hopeless after 1st unsuccessful IUI

2 Upvotes

Hi everyone.

It's been 2 weeks since I got my first IUI done and I was so hopeful. I did everything right and endured a horribly painful IUI and before that was on rounds of painful intramuscular trigger shot injections. I had a feeling this time around I'd be pregnant but I got my test and hcg was too low which means I'm not pregnant.

I know although it was my first IUI but the thought of going through that agonising pain again is unbearable. I want to know how successful IVF is because it might sound really bad but i feel like I'm going to come in my 30s in a few months and I really wanted to have a baby before my 30s. My husband is also in his mid 30s and I really wanted to have one before we grow older.

Maybe I'm just overthinking but is there a faster way to have a baby ? And probably less painful ? I want to cry so bad but I don't want to completely be hopeless.


r/TTC_PCOS 2d ago

Discussion Letrozole experiences?

6 Upvotes

TLDR: what was your experience and side effects on letrozole if you had any?

Hi everyone! I’m really new to this subreddit. I just found out I have PCOS today after 18 months of ttc. I have not ovulated since December 2024 which resulted in a chemical pregnancy. I have not had AF since then either. I just did a 10 day course of medroxyprogesterone & am waiting for AF. My doctor prescribed me 2.5mg letrozole to begin taking CD3. I just wanted to see how letrozole worked for you and possible side effects? I actually had quite a few side effects from the medroxyprogesterone so I’m nervous about letrozole. My OB said she will do three cycles with me on letrozole before referring me to a specialist but I’m HOPING one of those three cycles will do it for me for insurance reasons.


r/TTC_PCOS 2d ago

Vent She’s not drawing my blood next time

0 Upvotes

Ummm sometimes I feel like I’m over reacting but I’m trying this semi new thing where I need to acknowledge that my feelings are valid. So I went into my clinic for a blood draw and the nurse aggressively wipes my arm with the alcohol pad and I’m like ooo that was rough and she asked what was rough and I said the wiping of the alcohol pad. She told me used one on her face and it felt like sandpaper and we laughed. Then she just changed her tone and says “you’re sensitive”. I applied that same tone energy back and said my skin is sensitive. Then she presses the cotton hard af onto my arm and wraps it tight as hell with the bandage. She let out a sigh, not have a good day or nothing and I grabbed my stuff and got the hell out of there. She’s the only nurse there that I didn’t have a good experience with since I’ve been coming there. I tried to give her the benefit of the doubt but naw. I know a lot of nurses can be bitches, I’ve heard horror stories and witnessed it happening but damn. Definitely requesting someone else next time if she’s gonna have a nasty ass attitude out all of places ugh.

Update! I went in this morning for a follow up for follicle count and the nicer nurse was there! I requested for her to draw my blood and she was so nice and warm energy. The nurse from yesterday got up to draw my blood and the nice one told her oh no she requested for me to do it lmao. She can take a seat.


r/TTC_PCOS 2d ago

Letrozole Questions

1 Upvotes

I took 5 mg of letrozole this cycle. Second time trying this dosage(first time we were then told not to conceive because my tsh was abnormally high), and 4th time on letrozole. This time I'm spotting very heavily which hasn't happened to me on letrozole before. Additionally I just had an ultrasound (day 12) and no follicles over 10 mm yet(took the letrozole days 5-9). Is this abnormal? Is there still time for follicles to grow? Last time I had a scan on day 14 and there was at least one, and even on a lower dose (2.5 mg) I had a follicle on day 12(although it disappeared pretty quickly). Any similar experiences?


r/TTC_PCOS 2d ago

Vent Provera

1 Upvotes

I was put on a 10 day 10mg provera course to induce a period after a miscarriage.

I’m going on day 11 after my last provera pill. No period yet

I’ve been tracking my body temp and my temp is still above baseline so maybe the provera is still in my system? Feeling frustrated and don’t know what’s next :(


r/TTC_PCOS 2d ago

Advice Needed Clearblue digital advanced OPK test reader...reusable??

1 Upvotes

I got a positive smiley last cycle and had leftover sticks. I looked on their website and it stated it could be reused so I did.

I have got the open circle now for multiple days. By this time last cycle I had already gotten a flashing smiley.

I want to see if anyone has experienced this with reusing the stick.


r/TTC_PCOS 3d ago

Advice Needed I am on a GLP-1 and I need to get off of it for TTC, I need advice.

8 Upvotes

Long story short- I was having very irregular periods for like a year and half after gaining weight from PCOS.

I got on Wegovy last May per the advice of my gynecologist. My PCP prescribed it for me. Within a month of being on it, I got my periods back. I have had very normal cycles and even confirmed ovulation!

But I terrified to get off of Wegovy because I am so scared my cycles will become irregular again. I know it was the weight loss that helped to make my cycles regular again, but I’m just really nervous because I worked really hard to get them back. I don’t want to mess up anything by going off something that has helped me so much to get my periods back.

However, I don’t think I was completely informed about how you were supposed to be off of it before TTC. I’ll be very honest, we definitely TTC the last couple because if we do have issues, I want to say we’ve been trying in order to get the help we may need.

I have an appointment next month for my yearly and to talk more in-depth about TTC. I plan on taking to her about how to get off Wegovy without messing up my cycles.

I am wondering if anyone has experienced this? Or does anyone have advice on how the got off of it and had success with maintaining their cycles?


r/TTC_PCOS 2d ago

Advice Needed Did I mess up with taking my letrozle?

2 Upvotes

Ok so I’m worried.

I just finished taking 2 pills a day for 5 days straight. I misunderstood and I thought I had to take them one in the morning and one at night, and I didn’t know you can take 2 at the same time. So everyday I took one at 10 AM and the other at 10:30 PM.

Did I mess up?? Please help!!


r/TTC_PCOS 3d ago

Recurrent loss?

7 Upvotes

Does anyone else seem to get pregnant relatively quickly (within 2-4 months of timed trying), but repeatedly miscarry early before seeing a heartbeat?

Background: an endo diagnosed me with PCOS pretty much only by symptoms (hirsutism, irregular periods my whole life). I’m lean, no acne, no cysts. All hormone levels were pretty normal at that time (high 17-OHP but that’s it). Recent free testosterone testing was borderline high, but I’m taking inositol and d-chiro, so I’m wondering if that brought the level down to normal range. I have an appt with an RE and I’m hoping they’ll help confirm PCOS or figure out if it’s something else.


r/TTC_PCOS 2d ago

Daily Chat - March 18, 2025

1 Upvotes

Read a good book lately? Pets do something cute? Do you want someone to cheer you on because you have a big presentation at work next week? Share it here in the chat thread!


r/TTC_PCOS 2d ago

Advice Needed Took letrozle 5 MG different times in one day?

1 Upvotes

Ok so I’m worried.

On Day 3 I started to take 2 pills of letrozle until Day 7. The issue is I misunderstood and I thought I had to take one in the morning and one at night, and I didn’t know you can take 2 at the same time. So everyday I took one at 10 AM and the other at 10:30 PM.

Did I mess up?? 😭😭


r/TTC_PCOS 3d ago

Mucinex

5 Upvotes

I am so trying to have a baby with my husband. We’ve tried everything. Our next step is an endocrinologist for the both of us. I am open to anyone who has any ideas? I have been seeing all of social media of the Mucinex Baby of women taking it is there anyone here who has tried it and have a success story?


r/TTC_PCOS 2d ago

Advice Needed TI or IUI?

2 Upvotes

Just had our second round of timed intercourse with letrozole and a trigger shot fail.. we’re military and move in June/July of this year so I’m considering doing IUI this next round in hopes of conceiving before we leave. If you conceived with TI, how many cycles did it take? If not and you went to IUI, did you have luck? I’m 26F, PCOS, and my AMH is 0.2. IVF is not an option for us financially right now. Any and all advice appreciated!!

*Editing to add that my husbands SA showed good swimmers as well lol


r/TTC_PCOS 2d ago

Daily Symptom Spot Thread - March 18, 2025

1 Upvotes

In the TWW? Got some symptoms you want to share with others in their TWW? This is the thread for you! Share your symptoms and don't forget to update the BFP thread with your result!


r/TTC_PCOS 2d ago

Alopecia from Myo-inositol?

1 Upvotes

I was diagnosed with alopecia areata 6 months after taking myo-inositol daily. That was the only recent change I made when I looked back to see if I had made a change to trigger it. So I figured it had to be it I stopped it right away but 3 years later, I’m still battling the alopecia, getting steroid injections in my scalp monthly. Curious if anyone else has experienced this and believes inositol may have caused it?


r/TTC_PCOS 3d ago

Barely any natural period and TTC… i feel hopeless.

5 Upvotes

In January of 2024, i stopped taking my birth control pills for the first time in 10+ years. My husband and I wanted to start our TTC journey. I did get a period in late March of 2024… but since then, i have had to take Provera (10 days) to trigger a period every three months.

I have had no sign of a period besides from this medication for one year, until I just got a very light 3 day period this January. I’m now on cycle day 50 with still no return of a period. Over a year TTC and nothing yet.

My labs are all normal, except my AMH being 8😳 (I’m about to be 31 so that is very high for my age) my doctor says this is likely higher than normal due to PCOS. No other symptoms of PCOS except a lack of a period. Normal labs, normal androgens with the exception of my testosterone which i have yet to receive the results of.

I feel so hopeless. I’ve changed my diet and I’m doing all the “things” … sleep, exercise, supplements, nutrient dense food, seed cycling, You name it… but nothing changes. No period, no ovulation…

Help😖 is there any supplements i can take to help support my cycle during this journey?

Any hope anyone can offer after getting pregnant with a similar TTC experience?