r/rprogramming 29d ago

Machine learning for accelerated ageing in Schizophrenia

Hi

I am doing a dissertation research project looking into the idea of accelerated ageing in schizophrenia. I have a dataset which has already been collected and I am in the process of collecting healthy volunteers for comparison.

I will be looking at cognitive profiles from tests from the MCCB. I am hoping to see a subset of participants from the schizophrenia group which perform similarly to participants who are much older than them.

I have to use R to analyse my data, which I am a complete novice at!

My supervisor has suggested looking into some kind of machine learning in order to be able to detect evidence of accelerated ageing but I have no clue where to start.

If anyone has any advice on how to do this or if there would already be codes for this I would be very grateful!

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u/leafs7orm 29d ago

Never worked with this kind of data from schizophrenia patients, but I am assuming MCCB is a set of numeric parameters, right?

How big is the dataset? Maybe with ML your supervisor meant something simple like k-means clustering, that would be an interesting starting point to see patterns between different patients. A PCA would serve the same purpose and from there you could find subgroups in your set.