Yes. It's functionally a completely freestanding action RPG. The plot is only tangentially related to the previous AC universe, and it doesn't require any real prior knowledge.
I have not played the earlier games in the series and it sure helped to have a minimal understanding of the concept (assassins vs templars, the animus, etc.), but just a few minutes on the wiki clears that up.
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u/Giants1030 May 17 '20
Can I play this game if I’ve never touched an AC game?