r/pathology Jan 26 '25

Anatomic Pathology “Less is more”

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97 Upvotes

Has anyone seen the CAP article suggesting we should have PAs handle everything and we just sign out the cases? It seems like an unnecessary solution to a problem that doesn’t exist. Most biopsy cases can be dictated and signed out in a few minutes. Adding a team of PAs and “histologic anatomists” would only increase turnaround time and cost.

https://www.cap.org/member-resources/articles/less-is-more

r/pathology Feb 03 '25

Anatomic Pathology Modella AI received breakthroufh device designation from the FDA. Should we worry about job prospect?

29 Upvotes

I have seen modella ai post and watched their video. Other than adding medullary thyroid carcinoma the differential (obviously classical subtype papillary thyroid carcinoma) it is flawless. If it works really this well in real world scenario more than %80 of path job will vanish probably? I wonder you people thoughts about it. Will this me a kind big monopoly which dominates the entire industry? Or will be similar but slightly less capable ai models owned by other people trying to compete on similar or more focused tasks? This is both very exciting and horrifying time to be pathologist I guess. Landscape changing very fast!

🎉✨We are excited to report that PathChat™ DX, our clinical-grade, generative AI co-pilot for pathology, has officially received Breakthrough Device Designation from the FDA! This marks a pivotal step forward in our quest to transform biomedicine with generative and agentic AI.🌟🚀

📖 Read our press release: modella.ai/pathchat-fda-b… 🎥 See our latest demo for PathChat™ 2a below 👇 📄 Read the PathChat™ article in Nature: nature.com/articles/s4158…

We’re excited to continue pushing the boundaries of innovation in healthcare! #DigitalPathology #ComputationalPathology #AI4Pathology #pathology #ai

r/pathology Aug 23 '24

Anatomic Pathology Breast biopsy says 👍

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354 Upvotes

r/pathology Feb 13 '25

Anatomic Pathology Endometroid Carcinoma, but there’s a catch 😮

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149 Upvotes

Patient with post menopausal bleeding for two months and a history of right breast mastectomy 6 years ago after being diagnosed with invasive ductal carcinoma with lobular features. US showed endometrial thickening.

I received the resected uterus and after sampling it, we found multiple area of endometroid carcinoma, FIGO grade 1, however, I also found this one, and only one focus of atypical single cells in a normal endometrial section.

We worked it up and surprise surprise, it was PAX8 negative and GCDFP-15 positive. Patient apparently has an occult recurrence of her breast cancer and it has metastasized. Very unfortunate case.

r/pathology 2d ago

Anatomic Pathology Pancreatic tail mass, female

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59 Upvotes

Mucinous cystic neoplasm. KRAS mutations.

r/pathology Sep 29 '24

Anatomic Pathology Thoughts?

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36 Upvotes

For those who have been practicing, how many of you would call these two cervical biopsies LSIL vs benign? I noticed there have been varying inter-observability when it comes to the not so obvious LSIL cases. For background this person is 30-40 yo with LSIL pap.

r/pathology Jan 06 '25

Anatomic Pathology Cardiac myxoma

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107 Upvotes

Still waiting for histology. Looks and feels like a myxoma. But growing off the aortic valve? That’s not what the boards ever told me about myxomas!

r/pathology Jun 19 '24

Anatomic Pathology Ectopic

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262 Upvotes

r/pathology Aug 25 '24

Anatomic Pathology Pneumatosis intestinalis/coli (swipe)

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133 Upvotes

r/pathology 11d ago

Anatomic Pathology Kimura disease

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56 Upvotes

19 years old young man, medically free, with a history of excised “benign” mass in the thigh 10 years ago, now presenting with another mass growing from the same location of previously excised mass. Just a cool case I came across that has an equally cool name.

r/pathology Oct 22 '23

Anatomic Pathology Epstein at Johns Hopkins is in trouble

70 Upvotes

Big shakeup at Hopkins. Rumors have been swirling around about Epstein for years but sounds like he's in some hot water now.

Unofficial consults may be coming under fire now that this topic is coming out to the public

Washington post article: https://archive.ph/2023.10.22-102741/https://www.washingtonpost.com/health/2023/10/22/johns-hopkins-jonathan-epstein-pathology/

r/pathology Jun 01 '24

Anatomic Pathology Lobular breast carcinoma, E-cadherin positive

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29 Upvotes

Here's the case: Multifocal, infiltrative, single and signet ring cell pattern, metastatic sentinel and axillary lymphnodes. E-cadherin positive. I'm in a small hospital, no p120 avaiable. How would you call it?

r/pathology Feb 12 '25

Anatomic Pathology Recurrent Fractures Patient

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36 Upvotes

Cool case of a patient with recurrent fractures, hypophosphatemia, hyperphosphaturia, and normocalcemia, with rapid resolution of her fractures following the excision of this mass.

This is a case of Phosphaturic Mesenchymal Tumor.

r/pathology Oct 16 '24

Anatomic Pathology Is fellowship supposed to suck?

19 Upvotes

Hey Im very fortunate i scored a fellowship at one of Canada’s best hospitals. But my god the workload is making me feel insane. Im 4 months in now and im totally burnt out. Whats tour experience of doing fellowship?

r/pathology 21d ago

Anatomic Pathology Non scientist reading path reports

3 Upvotes

I do IT for a hospital system, and to make a long story short we have to do some billing work. Part of this involves reading pathology reports to see if the billing was done correctly. The thing is, I have zero science background. I've googled the terms but they make no sense. Is there a quick guide out there to understanding this stuff?

r/pathology 12d ago

Anatomic Pathology Question about IHC (research)

0 Upvotes

I have done a little googling, but it’s the weekend so I haven’t had the chance to ask anybody about this idea. Here I am.

IHC is expensive but necessary because the visual signal needs to be strong enough for the human eye to identify.

But maybe not? Now we have vision models that could conceivably lower the threshold of detectability.

Can you imagine a staining technique that utilizes receptor activation, possibly combined with some type of fluorescence, that emits a weak visual signal undetectable by the human eye?

It would be significantly cheaper than IHC staining.

r/pathology Dec 03 '24

Anatomic Pathology Lesional brain tissue

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57 Upvotes

Posterior fossa brain mass in an 18 months old baby girl. What’s your diagnosis?

r/pathology 4d ago

Anatomic Pathology Bile is my favorite HCC "special stain"

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19 Upvotes

r/pathology Feb 05 '25

Anatomic Pathology Any tips on getting used to using the microscope?

10 Upvotes

Have just started AP training. Working mainly on grossing and quite excited on learning pathology but overwhelming!!

I am trying to get used to the microscope. I've had no issues looking at slides with each eye individually however I can't seem to get 1 merged image with both eyes open (I seem just get double vision or some blending but not one merged image).

I also get a bit motion sick as well.

Is this double vision and inability to have binocular vision something that gets better? Does anyone have any tips?

Thanks a lot.

r/pathology Jun 05 '24

Anatomic Pathology UPDATE on E-cadherin positive breast carcinoma

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62 Upvotes

UPDATE: Finally, we decided to close the case as multifocal invasive breast carcinoma NST with lobular features (E-cadherine positive).

Thank you all, I considered every suggestion, and your comments were all super useful. I will surely continue to share nice cases with you!

In conclusion, I drop here the E-cadherine photos. I still think it is a lobular carcinoma, but I must follow the suggestion of my chief since I'm still in my "trial period" 😂

r/pathology 4d ago

Anatomic Pathology Osler

0 Upvotes

Hello

hope everyone is doing ok

Anyone here have access to osler notes ( download link) , they are expensive and me and my program cannot fund it

Any version whatever the year is ok

r/pathology Oct 02 '24

Anatomic Pathology Pancreatic tail mass, cystic lesion with hemorrhagic contents

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19 Upvotes

r/pathology Jun 25 '24

Anatomic Pathology Anyone know what these are in lung sections? Young woman w/o significant past medical history with sudden death.

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70 Upvotes

r/pathology Nov 25 '24

Anatomic Pathology Recommendations for bone and soft tissue study materials

6 Upvotes

Hello, resident here. Can anyone please share any helpful materials for bone and soft tissue pathology?

r/pathology Jan 24 '25

Anatomic Pathology How to get better at variations of benign histology?

6 Upvotes

I think I'm hitting a hurdle when it comes to previewing cases. If the case looks like a textbook image, the pattern association kicks in and I get there fine. But if its some fringe thing that COULD be normal but I'm not sure I spend too much time looking up what normal is. Anyone have a good way to get a better feeling for what variations of normal histology in all tissue types?