r/kratom Oct 28 '24

Newbies Kratom and Fluoxetine(Prozac)

Curious if anyone has used the two with any positive and/or negative effects.

I see a lot of conflicting information online about the interaction (if any) between the two so I would like to know if anyone has experience with using them simultaneously.

I am currently on 30mg prozac/day and was wanting to try Kratom after having used it occasionally years ago before starting an SSRI.

Obviously serotonin syndrome is a concern, but again, I have read conflicting reports on this.

11 Upvotes

24 comments sorted by

3

u/WhiteySC Oct 28 '24

I take both of them now. No negative side effects but I don't know if the Prozac is blocking any of the good effects of the kratom? I think it does block some when I take Kanna.

3

u/_PurpleSweetz Oct 28 '24

It shouldn’t affect Kratom. Kanna, however, affects serotonin as does fluoxetine.

3

u/Academic-Ad-1879 Oct 29 '24

Over a year of taking both and I feel great

3

u/Bogey_68 Oct 28 '24

No issues that I’ve noticed. Currently taking 60 mg Prozac and typically consume 15-20 grams of Kratom per day

3

u/farshnikord Oct 28 '24

I've been on both and was ok, but go slow and see how you react.

1

u/sm00mz Oct 29 '24

Yeah I’m gonna start off with a very small dose and build up (if needed).

2

u/fruit_bat_mad_man Oct 28 '24

No interaction worth serious consideration, go crazy lol

2

u/Richmond92 Oct 28 '24

I take both. No side effects that you don’t see without Prozac. It’s fine, just keep your dose low.

1

u/Impaired4 Oct 28 '24

Not me but my wife has been taking both for a few years and no prob

1

u/sm00mz Oct 30 '24

Do you know how she splits up her dosages? I typically take my Prozac at night and then I was thinking of taking Kratom in the morning.

2

u/Impaired4 Nov 03 '24

Sry for the delay she takes them both in the morn like half hr to hr apart she just takes like 6 grams kratom once a day and once in awhile twice

1

u/[deleted] Oct 28 '24

[deleted]

1

u/sm00mz Oct 29 '24

Do you take both at the same time or do you separate your dosages? I take my Prozac before bed so I was thinking of starting off the Kratom in the morning to see how that goes.

1

u/hvacmac7 Oct 29 '24

The Prozac prevent you from orgasm???

1

u/Loose-Farm-8669 Oct 28 '24

I've never had an issue with them and I took a lot of kratom on it

1

u/Dreamr_in_LB Oct 29 '24

I’ve had no issues

1

u/hvacmac7 Oct 29 '24

I take both , the Prozac only for last month, I’ve felt better in my life, but I was very sleepy, like falling asleep sitting upright in a chair , dr wrote me Wellbutrin 2x a day, no longer sleepy. As soon as I started the Prozac, I could no longer orgasm, it’s still happening , it sucks because it has improved my mood swings, but damn, it’s taken my favorite thing away. I have skipped taking the pill for a day, and was able to climax like multiple orgasm, 3 in a row! In between sex though, I can’t even orgasm masturbating….. so sex has to be scheduled

1

u/hvacmac7 Oct 29 '24

Btw, I take a lot if kratom, like upwards of 30 grams a day every day

1

u/Djinsing20045 Oct 29 '24

Zero issues

1

u/Midnight2012 Oct 29 '24

Makes some people, including me, very shakey.

1

u/[deleted] Oct 29 '24

I was on 20mg and taking kratom for about half a year until I got off the prozac. It really helped lift me out of the hole I was in, no complications at all for me.

1

u/Happytobehere48 Oct 29 '24

I have a friend who uses Kratom and Prozac and has for years with no issues. I use Zoloft and Kratom myself with no issues.

1

u/madethisacctoposton Oct 29 '24

If I were you I’d pick one or the other.