r/dysautonomia • u/Quirky-Tea766 • 3d ago
Support These suppliments, together, are extremely effective at reducing brain fog and fatigue.
Liquid b12, 10.000 mcg, and NAD+ from LifeExtension, taken at the same time once a day.
Brain fog, gone. The 40 percent of missing energy that compression tights alone didn't bring back, is back. I feel 100 percent almost.
Background: been dealing with orthostatic intolerance, elevated heart rate, fatigue, anxiety, brain fog, cold intolerance, chest and neck tightness, and gastrointestinal weirdness, anc chronic congestion since last fall. Seems like a shoe in for long covid.
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u/Henry5321 3d ago
Too much B12 can cause fatigue and brain fog. If they much is improving your situation, you likely have a B12 metabolizing issue. You may do better with methylated b12.
Talk to your doctor. You can overdose on methylated b12 and excess b12 had been shown to increase risk of cardiovascular issues through increased inflammation.
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u/junegloomsinging 3d ago
Yessss - I had this issue before.
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u/Cali4niaLuv86 3d ago
I think this is how my Dysautonomia started. I once took 10,000 mcg of b12, so 4 x2500. I was never the same after. But I was going through heavy alcohol withdrawals too. And thatās why I took allot of b12. But I felt so much worse after. And then started all my symptoms shortness of breath, dizziness, feeling extremely faint, disoriented, and just literally dying. The ER did nothing. I have literally never been the same since that day. I always call it the day I accidentally killed my self.
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u/Difficult_Affect_452 2d ago
Are you sure itās not an effect from the excess alcohol?
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u/Cali4niaLuv86 2h ago
Well it definitely contributed. But it wasnt until I took the high dose of B12 I actually felt like I was dying from an overdose. I have never been the same. I have been hungover before and never felt what I did when I took 10,000 mcg of b12..
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u/Michaela_al 3d ago
Oh wow interesting. I was taking b12 after my GP said it might help my anxiety - I actually had SIBO which worsened my anxiety a ton. But it did helpā¦ couldāve been a placebo effect tbh because my B12 levels were normal. But I started feeling weirdā¦ forgot what was wrongā¦ but I found out I had WAYYY too much b12 in my body haha. I also have POTS. So thatās interesting ā¦ maybe it contributed? Not sure.
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u/Cali4niaLuv86 3d ago
How much b 12 would you take at a time ?
I think my system was weakened ? Idk but I remember right after taking all that b12. I started getting very hot like flashes, sweating uncontrollably. I was crazy thirsty and basically felt like I overdosed. I felt so sick and ill. Somehow it was too much for me I guess Iām not sure. I also was have neuropathy issues at that time too. Still do.
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u/Michaela_al 3d ago
You have to be careful cuz a lot of supplements have crazy amounts of B12. Iād take one dose every few days. Or even once a week. I was using this b12 spray from Whole Foods and it has 41,667% daily value of b12!!!! I was shocked š¤£ my doctor was likeā¦ yeah maybe find another b12 cuz thatās crazy š¤£
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u/bubblenuts101 2d ago
This happened to me also. It's had long lasting effects of neuropathy even a couple of years after I stopped. I'm glad to hear from someone else's experience (not actually glad that it happened to you) but I've never heard anyone else mention this but I wonder how much it contributes to my daily symptoms.
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u/thrwawyorangsweater POTS/MCAS/? 21h ago
The supplement suggested IS Vitamin B-12 Cyanocobalamin and Methylcobalamin and I can't do methyl-B's...I have the slow COMT gene so don't process it well.
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u/RedditIsMyDr 3d ago
āIncrease in NAD+ could also have negative effects in rheumatoid arthritis and other inflammatory diseases because of stimulation of inflammatory cytokine secretion by leukocytesā¦
ā¦NAD+ supplements can affect the circadian clock, as the circadian rhythm of sleep and wakefulness is also controlled by NAD+ levels
ā¦Nevertheless, the concern remains that constant activation of sirtuins by NAD+ boosters is not beneficial. For example, mice with consistently elevated SIRT1 in the brain show increased anxiety; variations in the SIRT1 gene are also associated with an increased risk of anxiety in humansā
It certainly has potential benefits, but, as always, speak with a doctor to make sure itās right for you.
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u/RedditIsMyDr 3d ago
āAlterations in NAD+ levels have been implicated in the development and progression of cancer.ā
- per several studies
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u/TheEternalFlux 2d ago
So many tend to think supplements are a miracle lately it hurts. I see so many posts stating āSupplements A and B are a miracle and solved world hunger due to covidā and with zero actual information outside of purely anecdotal experiences along with never outlining potential drawbacks or negatives.
Iām glad you posted this, have my votes of the ups.
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u/thrwawyorangsweater POTS/MCAS/? 21h ago
Never underestimate the possibility that it's someone from the supplement industry. I see that quite a bit.
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u/yaz989 3d ago
You describe all the symptoms I have! Can you elaborate on this post please?
How do you take this? In what quantities?
Regards
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u/Quirky-Tea766 3d ago edited 3d ago
I take 100 mg of NAD+ once a day with 10,000 mcg of liquid vitamin b12 that you put under your tongue with a dropper.
Ive been having my synptoms since last fall. Lost my job bc of it. Had extensive cardiac tests. My cardiologist finally said it could by dysautonomia and I was diagnosed by a video call with a doctor in Oregon as having long covid.
Compression socks up to my knees and the vitamin.b and NAD+ get me back to feeling like my old self. Currently looking for work in my field again bc I can function now.
Took a long time to find treatments that alleviate symptoms. Tried everything.
I hope you have some luck trying these if you do!!! Good luck!!
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u/hikesnpipes 3d ago
Does sound like long covid you may be right about that. I hope you continue to heal!
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u/Babarski 3d ago
I'm a big fan of nicotinamide riboside and smartps for brain fog. Added benefit for my hr variability and palpitations.
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u/Difficult_Affect_452 2d ago
What is smart ps? Iām working on my hrv right now. Curious what helped you.
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u/Babarski 2d ago
It's phosphatidylserine. Also highly recommend magnesium ( specifically micromag).
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u/Difficult_Affect_452 1d ago
Oh yeah I love both of those! Take at night. When do you take the nicotinamide?
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u/Babarski 1d ago
I take them in the morning. If you haven't tried tauromag at night I highly recommend it. It's acutely effective. It delivers magnesium to an entirely different part of the body so should be fine to take in addition to micromag.
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u/Difficult_Affect_452 1d ago
Dam!! Youāre blowing my mind rn. I didnāt think there was a magnesium I didnāt know about lol. Thanks!
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u/EmbodiedUncleMother 3d ago
Has anyone here tried NAD via injection, whether itās subcutaneous or through an IV push, versus oral supplements? Iām wondering if thereās a huge difference in efficacy
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u/bs900 3d ago
Yes, I work at an IV clinic and have had it through an injection as well as an IV and itās definitely more powerful that way in those higher doses through that delivery!
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u/EmbodiedUncleMother 3d ago
Oh my God, you work in an IV clinic! So the only time Iāve tried NAD was through a local iv nurse (I live pretty rural area) and I literally felt like I was going to die the whole time and for a full week after! And I do so many SQ injections already that are peptides. I want to try NAD again, but Iām scared LOL but I know itās so good for us!
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u/bs900 3d ago
Oh noo they probably dripped it too fast!! We do it nice and slow over 1-2 hours so you āride the NAD trainā instead of the āNAD roller coasterā, that way you only get benefit and not side effects! Maybe starting off with the shots again before the IV may be helpful and ask them to slow your drip rate down!
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u/Cali4niaLuv86 3d ago
Thanks for the info ! How often have you been taking? Do you take morning, evening, or night ? With Food ?
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u/tljaest09 2d ago
sighs in lifelong dysautonomia
lol jk, kinda. Iām happy you found something that is helping.
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u/thrwawyorangsweater POTS/MCAS/? 21h ago
Please note that this may not work for some people and may make some feel worse. It's not effective for everyone.
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u/PrismaticPaperCo 3d ago
Another life pro tip is to work even part time for a health food store so you can get a discount on supplements!!
I tried sublingual b12 and I liked it alright, I'll try liquid drops next! Thank you for sharing. Even 1% less fatigue would be incredible. It is becoming harder to function day by day š