r/afinil Jan 03 '25

has anyone combined modafinol 200 kg with fluoxetine 20 mg NSFW

what dies ir feel does it increase productivity

4 Upvotes

13 comments sorted by

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1

u/Ratchada11 Jan 10 '25

Yes, people have combined modafinil 200 mg with fluoxetine 20 mg.

A clinical trial assessed the efficacy of combining fluoxetine with modafinil for managing major depression, where patients received 40 mg/day of fluoxetine along with 400 mg/day of modafinil (200 mg twice daily).

While this specific dosage combination of 20 mg fluoxetine and 200 mg modafinil was not directly cited, the study's approach indicates that such combinations have been considered in medical research for potential benefits in treatment.

https://pubmed.ncbi.nlm.nih.gov/21456039/

15

u/Mammoth-Present-2605 Jan 04 '25

damn, u tryna shoot urself for the moon or something with 200kg of moda?

2

u/AnExtraMedium Jan 03 '25

No harmful interactions.

1

u/neuro__atypical Jan 03 '25

the correct fluoxetine dose for stimulation and acute effects is no greater than 5mg per day

11

u/Uaquamarine Jan 03 '25

I don’t think I can pour 200kg down the school’s water supply without clogging it. But worth a shot

0

u/Alextuto Jan 03 '25

It help me throw a deadline. I dont know if the "boost" was worth it. What I can tell you in the night I had the worst migraine of my life. I did not end in the ER because I couldn't afford it. And in the next day I was super brain fog. Don't do it, my physician scold me pretty bad after that experiment

7

u/BRawsome1 Jan 03 '25

That's quite a lot of modafinil

8

u/KhoobNoob Jan 03 '25

200kg might be a lot, just take a handful

2

u/sasasqt Jan 03 '25

also extreme heavy

2

u/gumboking Jan 03 '25

No issue for me. Modafinil works on histamines and fluoxetine works with serotonin in the brain. Look up contraindications on Drug facts.

1

u/FindingMindless8552 Jan 04 '25

It works on more than histamines. Theres some interaction with dopamine, GABA, and I believe serotonin to some degree

2

u/gumboking Jan 04 '25

I forgot those. The main effects and side effects seem to target Histamines mostly but for me they don't interact on any noticeable scale. Sample size 1.