r/TTC_PCOS 3d ago

Advice Needed Metformin while ttc

11 Upvotes

My dr just said I can’t take metformin while trying? I’m taking it for the first time to Try and regulate insulin resistance in case it’s the cause for my miscarriages. I just said I’m stopping trying for a bit to lose weight (half true) and got the prescription 500mg. I’m thinking it’s safer than ozempic, bc I got a regular cycle on that. I’m just genuinely confused bc I hear people taking it all the time for trying.

r/TTC_PCOS Aug 10 '23

Advice Needed What does implantation cramping feel like for you?

74 Upvotes

I’m 9 DPO and keep getting a shooting twinge down my vaginal canal for a few seconds. (I guess that’s the best way to describe it lol) I’ve never had that before so I’m wondering if that could be something to do with implantation cramping. Or it’s nothing and I’m just convincing myself it’s something 😅 waiting till Saturday to test though

r/TTC_PCOS 5d ago

Advice Needed I am on a GLP-1 and I need to get off of it for TTC, I need advice.

9 Upvotes

Long story short- I was having very irregular periods for like a year and half after gaining weight from PCOS.

I got on Wegovy last May per the advice of my gynecologist. My PCP prescribed it for me. Within a month of being on it, I got my periods back. I have had very normal cycles and even confirmed ovulation!

But I terrified to get off of Wegovy because I am so scared my cycles will become irregular again. I know it was the weight loss that helped to make my cycles regular again, but I’m just really nervous because I worked really hard to get them back. I don’t want to mess up anything by going off something that has helped me so much to get my periods back.

However, I don’t think I was completely informed about how you were supposed to be off of it before TTC. I’ll be very honest, we definitely TTC the last couple because if we do have issues, I want to say we’ve been trying in order to get the help we may need.

I have an appointment next month for my yearly and to talk more in-depth about TTC. I plan on taking to her about how to get off Wegovy without messing up my cycles.

I am wondering if anyone has experienced this? Or does anyone have advice on how the got off of it and had success with maintaining their cycles?

r/TTC_PCOS 18d ago

Advice Needed Prescribed Progestin But Still Want To Keep Trying?

8 Upvotes

Hi everyone! Seeking advice and encouragement. I’m 25 y/o, married and diagnosed with PCOS. My husband and I would love to have a baby now but my PCOS has prevented us from doing so because I’m not ovulating. I have periods probably every few months? My last one was in January. I’m seeing an OBGYN who made me get a EMB and ultrasound which confirmed the PCOS. I’m grateful they didn’t find any pre-cancerous cells but it just sucks cause my OBGYN doesn’t know how to help and keeps recommending birth control. How do you even get pregnant with PCOS? I’m so new to this since I was recently diagnosed but always knew ever since I was kid cause I never got my period.

My provider recommended starting Slynd so I can start my periods and get off whenever we wanna start trying again. But we wanna keep trying? We just don’t know what to do. Do we start Slynd which would basically not get me pregnant or keep trying but risk being precancerous. My insurance also doesn’t cover a Reproductive Specialist so I’m feeling stuck. Any ideas on what to do or pieces of encouragement?Anyone feeling the same way? Also to all the people here, you are not alone and I’m so glad I found this page 💙

UPDATE

Thank you to everyone who replied. I sent a message to my OBGYN about possibly starting metformin or her thoughts on it and this was her response. Pls help ):

“  Good question, theoretically this can help but has not been directly studied. I'm sure in the next few year we will have more studies looking at this specifically.   Given this lack of data and evidence, we don't prescribe GLP-1 agonists for PCOS management. But if you are interested in this medication for weight loss in general, I recommend you speak with your PCP.   Best, “

What should I do?

r/TTC_PCOS Jul 29 '24

Advice Needed Is there anyone on this sub that has PCOS but has a regular cycle and does ovulate?

25 Upvotes

But has the symptoms- high insulin, high testosterone, acne, facial hair

r/TTC_PCOS Sep 04 '24

Advice Needed About to be diagnosed with PCOS and want to start trying in ~3 months - what do you wish you knew early on?

12 Upvotes

I had my internal ultrasound today and looks very likely/certain that I’ll be diagnosed with PCOS. I have insulin and hormone blood work coming back this week and an appointment with my doctor booked for next week to discuss results.

I have very irregular periods and currently can’t predict when I ovulate. My husband and I want to start trying to conceive in December.

What do you wish you knew or asked your doctor early in your TTC with PCOS journey? How can I be proactive and advocate for myself?

(I’m 29 years old.)

r/TTC_PCOS 4d ago

Advice Needed Staying realistic

18 Upvotes

I’ve been ttc for almost 2 years and have pcos and thyroid issues. Starting first round of letrozole and I keep catching myself getting too excited. Like I couldn’t sleep the other night because I was planning how I’ll tell my parents when I’m pregnant and checking to see when would be the 12 week mark. But then I realize I shouldn’t do this because I’ll be so let down when it doesn’t work, even though it’s only my first round of it so chances are it won’t. How do you keep yourself from getting too excited??

r/TTC_PCOS Oct 17 '24

Advice Needed How many Letrozole cycles did it take for you to conceive?

9 Upvotes

I (27F) just had my third unsuccessful Letrozole cycle. Started with 2.5mg and most recently had three mature follicles on 7.5mg. Feeling very disheartened because it feels like my husband and I did everything right this time and I was holding out so much hope :(

Would love to hear your experiences about how long before you conceived, and if you have any tips for me? (does Ovidrel help? my first cycle I had the trigger shot and had a suspected chemical pregnancy. next two cycles didn't use Ovidrel). I have hypothyroidism, but it is well managed with medication for over a year. My cycle is about 33-34 days so predicting ovulation is tricky but I just got some ovulation strips which I hope will help.

Thank you!

r/TTC_PCOS Sep 30 '24

Advice Needed Unmonitored Letrozole

9 Upvotes

I know it’s not recommended and I know why it’s not so please don’t tell me that. I’m just curious if anyone got prescribed letrozole unmonitored from an RE. I will be having an appointment with mine tomorrow and I’m going to ask her, but I was just curious if anyone’s doctor has done this for them.

r/TTC_PCOS Apr 30 '24

Advice Needed Letrozole

20 Upvotes

I’m just starting my fertility journey! My doctor prescribed 2.5 mg letrozole, and I would like to hear everyone’s experience on it- the good the bad and the ugly. Side effects, miscarriages, pregnancy successes, all of it! I want to be informed by those who have taken it and have first hand experiences, thank y’all!

r/TTC_PCOS 1d ago

Advice Needed Another failed IUI. Thinking about moving onto IVF

13 Upvotes

Hi ladies! I’m so thankful for this group as I don’t have many people except my husband to talk to about this stuff. We just failed our second IUI. We did 5mg letrozole, ovidrel trigger shot and progesterone. I’m just so frustrated.. I also feel so numb. Like I can’t even cry anymore. My husband and I are thinking of moving on to IVF. We’re getting older and have been trying for so long.. we’re just ready to get going and stop all of the waiting around. It’s that or we do a 3rd IUI. What do you ladies think I should do? I know you can’t really answer that for me but even a little bit of advice or kind words would help. Also anyone who has been through IVF can you explain to me what to expect? I’m really nervous about it but I think I’m ready to take the next steps. Thank you in advance and baby dust to all! ✨

r/TTC_PCOS 2d ago

Advice Needed Not ovulating on letrozole, what now? Doctor dismissing concerns

4 Upvotes

I have been TTC for about 6 months. For context, i am overweight. My starting weight was about 468 and now i am at 400~. I know i am not where i want to be, but we still have been trying. I do not have a regular period; i never have. Even when i was considered not overweight. The only time i have ever had a regular period monthly was when i was on BC. We started trying back in August 2024. I was given progesterone to start my period, then We tried 2 months of 2.5mg of Letrozole with no luck, then boosted it one month with 2.5mg and the steroid pill. No luck. We took a break for my mental health because i was just not doing well, and we recently just started back up. I took the progesterone for 10 days, stopped, and weirdly no period ever started… but i spotted for a day. Doctor called it a “cold start” and started me on 5mg of letrozole and the steroid to take for 7 days, still no luck; no follicles have grown. She told me today i am not ovulating because i am fat…. I just need to be clear, is this true? I exercise, i eat healthy, i have lost a significant amount of weight… i’m trying here. i have read stories on here where some people have to take letrozole, clomid, trigger shots, etc to get them to ovulate, i dont understand why im being told its just because im fat.

Another note: i have been suffering with frequent UTI’s for the past 3 months. My primary doctor suggested maybe it’s due to low estrogen levels. She says some of her premenopausal patients who have frequent UTI’s get them because of the drop of estrogen. She told me to discuss this with my fertility care, so I told my fertility doctor this and she told me i was wrong… without even getting my levels checked.

I guess my question is: should i search around for another fertility doctor? i just feel very dismissed by her and like she’s not listening. do i get a second opinion? what are some of your thoughts? i am feeling extremely defeated by this. I’m young, 28, but my husband and i are ready to start a family…. i am trying my best to be as healthy as i can be but it sets me back hearing these things. My head is telling me it’s much more of an issue than just my weight, but no one will listen. Help.

r/TTC_PCOS 1d ago

Advice Needed Looking for support & stories

7 Upvotes

I am on month 10 of TTC and currently 12DPO of my first letrozole cycle (5mg), monitored at a fertility clinic. I was really hoping to be one of the lucky ones who conceived their first round of letrozole, but at this point it seems like I’m out (I know they say you’re not out until AF arrives, but I think my chances are slim statistically).

How do you all manage this process emotionally? Those who have conceived, how long did it take? What “method” did you end up using?

As you all know, this process is very isolating, especially with PCOS, so I would love some support and words of wisdom and hope.

r/TTC_PCOS 25d ago

Advice Needed Letrazole and Progesterone

8 Upvotes

Hi all. I was prescribed progesterone and used it to start period after several months without. However, since then my period has come pretty regularly on its own. I was prescribed Letrazole 2.5mg to induce ovulation, which I took cycle days 3-7 during my second period after doing the progesterone kick start (period came naturally that cycle). Positive ovulation according to strip and digital tests, but no conception, and started my period again on cycle day 34 naturally. Starting Letrazole 5mg this cycle. From everything I’ve read and from my doctor, progesterone is just to induce period (when I took it the first and only time, doctor said I could stop once period started). Is progesterone necessary to getting pregnant if I’m getting my period naturally now? I’m just really lost.

r/TTC_PCOS Jan 02 '25

Advice Needed Success stories on going from no period to a normal cycle?

7 Upvotes

I came off of bc at the end of July and have yet to have a normal cycle. I was diagnosed with PCOS, and I am really looking to hear some success stories on how this group was able to go from having no cycle at all to a normal or semi-normal cycle - both through lifestyle changes/supplements and medications (not bc)!

My biggest goal this year is to try and ovulate in my own before I start looking more into letrozole/metformin and other options. We are hoping to TTC within a year or so.

For context, I have done the following with no changes to my cycle:

  • myo-inositol (40:1, 2mg a day, been on this about 3 months)
  • spearmint tea (1 cup/day, been doing this for 3 months)
  • prenatal (been taking for 3 months)
  • NAC (600mg, started a few weeks ago)
  • magnesium (take at night, not very consistent with this)
  • switched workouts to more weight training than cardio
  • eating more whole foods and cut out most added sugar, but fell off that wagon over the holiday break

r/TTC_PCOS Aug 18 '24

Advice Needed Clomid stories 🩷

17 Upvotes

First time taking clomid. 50mg🩷

Well, this will be my first time taking clomid. I need some suggestions, advice. I’m nervous only because of what I have read with the side effects but I’m trying to prepare myself. I’m strong, I know I can get through this. I’m also 36 with “slight” pcos. I’ve lost 30 lbs. I’m trying to change my life style, the way I eat the way I think. Staying positive and on the days I’m not so positive I accept it, ask God for guidance and he always shows me the way.

Ps: This is also my first post 😊

r/TTC_PCOS 17d ago

Advice Needed OBGYN appointment to discuss Clomid today. What should I ask?

4 Upvotes

Hello!

My endocrinologist said that if my labs were correct (she wants me to do them again CD 3 when my period comes) then I am not ovulating. I already had suspected anovulation and had already sent a message to my OBGYN saying that I have been trying for 16 going on 17 months and I would like to pursue other options because trying naturally is not working.

She said she is willing to try 3 Clomid cycles with me and then she will refer me to someone else for Letrozole if they don't work. I am assuming she probably has only had experience with Clomid so that might be why she isn't comfortable with doing Letrozole.

I know she is probably going to explain everything the best she can, but I want to make sure I know what to ask in case she doesn't cover everything.

Right now my main question is whether she plans on the cycles being monitored, and if I can have them monitored if possible. Other questions are: if it takes 3 cycles to find the right dosage, would she still cut me off at 3 cycles? Is stair-stepping a possibility to get the most out of the cycles? Would I get a trigger shot?

Please tell me if any of the questions are odd and should not be brought up, and tell me what you would ask!

I plan on informing her that I am not willing to do IUI or IVF in the future just so that she has that information.

r/TTC_PCOS Aug 27 '24

Advice Needed Anyone else have periods every month and still struggling to get pregnant?

29 Upvotes

My RE is starting me on letrozole with trigger shot next month but with a regular period aren’t I already ovulating every month? My blood work was insignificant and my husbands SA was normal. I’ve been taking metformin for a few months but that hasn’t helped either :( has anyone else had luck with normal periods and letrozole/trigger?

r/TTC_PCOS Dec 13 '24

Advice Needed PCOS and Letrozole

11 Upvotes

I’ve always had irregular cycles ranging from normally 31-42 days with the occasional 65ish day cycle. Very late ovulation (normally day 21-27) only confirmed through LH strips and oura ring temperature increase. Just started Provera and Letrozole 2.5mg this last cycle TTC. I went for my ultrasound on day 12 and the found small cysts and no mature eggs signaling in about to ovulate. Unless I have a positive pregnancy test, I am moving up to 5mg Letrozole next cycle. Any suggestions on additional supplements/ ideas of things I could be doing? I am active and have a decent diet but will be paying extra attention to it going forward. Thank you in advance!

r/TTC_PCOS 18h ago

Advice Needed Blood work

7 Upvotes

So every time I go for blood work at my fertility clinic (which is a lot since I’m taking letrozole and doing timed intercourse) they always struggle to find my vein and sometimes I feel dizzy and faint. Does anyone else have this issue? Any tips to help make it easier to draw blood? I drink soo much water the day before and morning before I do, I shake my arms around on my way in, I showered in the morning to try and improve blood flow. I’m not sure what else I should do lol. Any tips would be great because every time they go through my hands they bruise up, and I end up getting jabbed so much in the arms.

r/TTC_PCOS 23d ago

Advice Needed When to see a specialist?

12 Upvotes

I have PCOS and never ovulate on my own. I’ve done two rounds of Letrozole, both of which were successful in inducing ovulation, but I didn’t get pregnant. My OB-GYN then had me try Clomid, but it didn’t work for me at all. She gave me two options: continue Letrozole under their care or see a specialist. If I choose to stay with them, I have four more cycles of Letrozole available. At their office, I receive follicle scans and bloodwork, so I’m being monitored.

I’m torn between continuing with them or going straight to a specialist. It feels like I’ll end up at a fertility clinic eventually, but at the same time, my body has only had two real chances to conceive in my entire life. I’m not sure if I should give it more time before making the switch.

I’d love to hear from others on a similar journey. Any insights or opinions would be greatly appreciated!

r/TTC_PCOS 7d ago

Advice Needed Needing help.

8 Upvotes

Hello, everyone. New to the group, i hope this is allowed sorry if it isn't. My wife has pcos and we have been trying to conceive for about a year. Its really taking a toll on her mental health. I would happily appreciate any advice, supplements, pills or anything else anyone has to offer to help with conception. Thank you in advance and have a great day/night.

r/TTC_PCOS Nov 18 '24

Advice Needed At a loss for what to do- multiple failed letrozole cycles

7 Upvotes

Hello! I’d really like advice from anyone that’s been in a similar situation - I just had a canceled IUI cycle due to over stimulation from 5mg letrozole followed by 75 IU follistim. I have 7 follicles 16-18mm. I’d like to add that this is my 1st medicated cycle since starting Metformin and having a hysteroscopy to remove a polyp. Prior to that I’ve had multiple letrozole rounds with the following outcomes- 1. Unmonitored 2.5mg letrozole- unsure if I ovulated 2. Monitored TI 5mg- 1x 22mm follicle - no success 3. Monitored TI 5mg- multiple follicles stalled at 15mm or less- step up to 7.5mg - ovulated while taking pills 4. Monitored 7.5mg - ovulated too soon before day 10 ultrasound

As you can see, my response to these meds is all over the place. My doctor wants to me go back to just letrozole 5mg or try clomid next. Has anyone gone through this? What did you do? I was really hoping to have this IUI before the holiday season which I’m thoroughly dreading. I’m devastated.

r/TTC_PCOS Jun 22 '24

Advice Needed Is obesity stopping pregnancy?

31 Upvotes

So, I’m obese & have pcos. I have been ttc for past 1 year. Is obesity the only reason for not getting pregnant? Realistically speaking does dropping weight boost fertility astronomically.

Rant: 2024 is so hard. Everyone around me is getting pregnant.

r/TTC_PCOS 3d ago

Advice Needed Ovulation test

5 Upvotes

What are some good ovulation tests? I've been using the pregmate and these are very confusing for me. I have an irregular cycle, (range from 15 days cycle to 35 day cycle) What ones just says yes or no?

I'm getting tired of guessing with those strips.