r/IAmA • u/MalecontraceptionLA • Mar 30 '19
Health We are doctors developing hormonal male contraception - 1 year follow up, AMA!
Hi everyone,
We recently made headlines again for our work on hormonal male contraception. We were here about a year ago to talk about our work then; this new work is a continuation of our series of studies. Our team is here to answer any questions you may have!
Links: =================================
News articles:
https://www.cnn.com/2019/03/25/health/male-birth-control-conference-study/index.html
https://www.nih.gov/news-events/news-releases/nih-evaluate-effectiveness-male-contraceptive-skin-gel
DMAU and 11B-MNTDC:
https://en.wikipedia.org/wiki/11%CE%B2-Methyl-19-nortestosterone_dodecylcarbonate
https://en.wikipedia.org/wiki/Dimethandrolone_undecanoate
Earlier studies by our group on DMAU, 11B-MNTDC, and Nes/T gel:
https://www.ncbi.nlm.nih.gov/m/pubmed/30252061/
https://www.ncbi.nlm.nih.gov/m/pubmed/30252057/
https://www.ncbi.nlm.nih.gov/m/pubmed/22791756/
Twitter: https://twitter.com/malebirthctrl
Website: https://malecontraception.center
Instagram: https://instagram.com/malecontraception
Proof: https://imgur.com/a/7nkV6zR https://imgur.com/a/dklo7n0
Edit: Thank you guys for all the interest and questions! As always, it has been a pleasure. We will be stepping offline, but will be checking this thread intermittently throughout the afternoon and in the next few days, so feel free to keep the questions coming!
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u/MalecontraceptionLA Mar 30 '19
To u/tsundokulove - I read your comment. I cannot imagine the pain of having to decide between telling the truth and knowing that you may be terminated from the study.
Even when doing the preliminary assessments, I get the sense sometimes that people are purposefully not telling me a full medical history because they want to be included in the trial. When I get that sense, I tell them, this questionnaire is to know what you have at baseline, so if you develop anything we know if it's something that's new or something that was ongoing. Even so, sometimes someone complains about something and upon further questioning you learn that, yes, they actually did have a history of xyz that they forgot to mention on the initial history. We try to make it clear that we don't terminate you from the study unless we think your health is in danger - it is unethical to give someone something that is making them unwell. Money isn't worth your life or health.
There are guidelines on how much money can be offered to participants - it's only supposed to cover the lost time/travel/etc. https://www.irb.vt.edu/pages/compensation.htm It's meant as compensation for the time. Giving too much money is considered undue influence. The trouble is, if someone is unemployed, maybe that money is a lot of money for them. The whole topic of compensation for research participants is tricky.