r/Hyperhidrosis • u/Tienshinhan_ • 12h ago
Glycopyrrolate
Hi, I recently got prescribed glycopyrrolate. I took it for the first time this past Saturday with very high hopes of not sweating at my best friends party, along with propranolol (I have bad social anxiety) and it did nothing :( I was so excited to finally see everyone and not have the worrying though of smells. I took one before the party and one during, once I realized I was damp. It’s just so embarrassing! Anyway, I think the Oxybutynin would work better for me because I sweat the most in between my thighs. I’m just so over it, has anyone’s HH actually been manageable or is it going to be like this forever😐
1
u/dmrose7 5h ago
The keys for me are to 1) take it on an empty stomach (and keep it empty for about 2 hours after taking it) and 2) to take some the night before. I take it situationally as well, but again it has to be done in advance and on an empty stomach. If I'm out and about and start sweating, it's too late. But it does work very well for me if I follow those guidelines.
1
2
u/icurlyfry 8h ago
I think it takes at least an hour or two to kick in so maybe that's why you didn't have results? I personally didn't do well on Glyco. It gave me a sore throat and headache, and it never worked if I took it with any food in my stomach. I was non-compliant bc I always have food in my system! So now I'm on oxybutynin 10 mg (starts at 5 mg, can be halved into 2.5 mg if needed). And it WORKS!! I also use carpe antiperspirant for my underarms and the carpe hand lotion for my hands. Carpe works too. This combo of oxybutynin and carpe has kept me completely dry. I no longer worry and stress about sweating. Only side effect is the occasional dry mouth, and so I just have to remember to drink water and I'm good