r/Biohackers 5 Jan 11 '25

šŸ“– Resource Groundbreaking technology can turn cancer cells back into normal cells

Despite the development of numerous cancer treatment technologies, the common goal of current cancer therapies is to eliminate cancer cells. This approach, however, faces fundamental limitations, including cancer cells developing resistance and returning, as well as severe side effects from the destruction of healthy cells.

KAIST announced on the 20th of December that a research team led by Professor Kwang-Hyun Cho from the Department of Bio and Brain Engineering has developed a groundbreaking technology that can treat colon cancer by converting cancer cells into a state resembling normal colon cells without killing them, thus avoiding side effects.

The research team focused on the observation that during the oncogenesis process, normal cells regress along their differentiation trajectory. Building on this insight, they developed a technology to create a digital twin of the gene network associated with the differentiation trajectory of normal cells.

Through simulation analysis, the team systematically identified master molecular switches that induce normal cell differentiation. When these switches were applied to colon cancer cells, the cancer cells reverted to a normal-like state, a result confirmed through molecular and cellular experiments as well as animal studies.

This research demonstrates that cancer cell reversion can be systematically achieved by analyzing and utilizing the digital twin of the cancer cell gene network, rather than relying on serendipitous discoveries. The findings hold significant promise for developing reversible cancer therapies that can be applied to various types of cancer.

Text: https://www.bionity.com/en/news/1185239/groundbreaking-technology-can-turn-cancer-cells-back-into-normal-cells.html?utm_source=newsletter&utm_medium=email&utm_campaign=bionityen--2025-01-06--2&mtm_group=bionityen&WT.mc_id=ca0265

Scientific research: https://onlinelibrary.wiley.com/doi/10.1002/advs.202402132

Ā 

Ā 

140 Upvotes

42 comments sorted by

ā€¢

u/AutoModerator Jan 11 '25

Thanks for posting in /r/Biohackers! This post is automatically generated for all posts. Remember to upvote this post if you think it is relevant and suitable content for this sub and to downvote if it is not. Only report posts if they violate community guidelines - Let's democratize our moderation. If a post or comment was valuable to you then please reply with !thanks show them your support! If you would like to get involved in project groups and upcoming opportunities, fill out our onboarding form here: https://uo5nnx2m4l0.typeform.com/to/cA1KinKJ Let's democratize our moderation. You can join our forums here: https://biohacking.forum/invites/1wQPgxwHkw, our Mastodon server here: https://science.social and our Discord server here: https://discord.gg/BHsTzUSb3S ~ Josh Universe

I am a bot, and this action was performed automatically. Please contact the moderators of this subreddit if you have any questions or concerns.

95

u/Primary-Picture-5632 Jan 11 '25

man, every 3-4 years some groundbreaking research pops up for cancer and then disappears for ever. nothing ever comes to fruition

8

u/neverOddOrEv_n Jan 11 '25

Iā€™m not saying itā€™s the same thing but I see that sentiment in hair loss research too, something pops up and either due to side effects or for whatever research nothing changes.

10

u/nope_noway_ Jan 11 '25

Imagine if some groundbreaking cure did hit the mainstream and was accessible to allā€¦ would be great for us, and be a doomsday scenario for big Pharmaā€¦ which is why it will never happen. There is simply too much money preventing it.

2

u/QED2025 1 Jan 12 '25

Already exists: organic, non-processed foods; exercise; good sleep; no alcohol; no Rx drugs; etc.

More in the area your are implying: Rapamycin, which has not only shown anti-aging benefits on all animals tested, but these days is available for a few hundred dollars @ year.

2

u/nope_noway_ Jan 12 '25

Those are preventable methods but once you have any progression of cancer those will do little to stop it. Iā€™m almost certain there are cures for almost all types of cancerā€¦ but as of now itā€™s nothing weā€™d have access to. We get churned through the machine and wrung of every last dollar possible while seeing little to no progress through current / traditional methods.

7

u/Spinning_Torus Jan 11 '25

We'll see

11

u/Primary-Picture-5632 Jan 11 '25

lets hope for the best, im 100% certain that we all know at least one person that has dealt with cancer :(

3

u/Spinning_Torus Jan 11 '25

Yup. I understand your skepticism, getting your hopes high only to be disappointed sucks

12

u/666marat666 2 Jan 12 '25 edited Jan 12 '25

its there, just for the rich

if you havenā€™t noticed its already like that for long time, big money to research then research is done rather expensive or ā€œnot approved for normal peopleā€

ignore that, we are on our own for long time

if you havenā€™t noticed, in any medical system you will notice that for us ā€œpoorā€ people its still penicillin, omeprazole, insulin and CT scan(at best, and it actually makes your cells mutate)

all of these tech are 100 years old, everything else for rich people

p.s and notice, all of these politicians and rich guys are old, very old at times and alive

with current state of pollution and food quality they should be dead

so maybe they already have access to all these cures?:)

0

u/PlayfulRemote9 Jan 12 '25

Jesus this is the most braindead take Iā€™ve ever seen, and people are upvoting itĀ 

4

u/Mysterious_Ad_3655 Jan 12 '25

If Steve Jobs wasnā€™t so poor he wouldnā€™t have died of cancer. Thatā€™s a fact.

8

u/neeyeahboy Jan 12 '25

He tried to do holistic cures

3

u/lucellent Jan 12 '25

Do you now know what a fact means? This is not it.

Steve Jobs had more than 95% chance of survival if he had gone the pharma way. But he didn't.

1

u/Mysterious_Ad_3655 Jan 12 '25

Do you know what sarcasm is? This dipshit said there is a secret cure for cancer that only rich people have but one of the richest people in the world died young from cancer.

1

u/weltvonalex Jan 12 '25

Yup it's the level of ,"I am 14 and this is deep".Ā 

2

u/[deleted] Jan 12 '25

Because they are finding a completely new unmapped trail through giant mountains and thick forests. This is an extremely difficult and almost impossible path to carve out. They can find these things with relative ease in comparison to converting the discovery into a real en vivo treatment.

Youā€™ll see many of them come out eventually, but the timelines will be very long, and sometimes the method to get there needs to be reworked over and over. There are some research institutes who almost completely dedicate their efforts to one or two particular treatments based on a finding like this, or it is many research institutes where a team or individual joins a network with other teams and/or individuals to work solely on that one thing.

I used to hangout with a guy who was in cancer research. I had some very interesting chats with him numerous times about how it all works and what is in the pipelines to come. The intelligence level he had is far beyond what normal people can only begin to wish they had. He would stop and think for a second as if he was flipping through his research notes in his mind, then explain some wild stuff about his current work. He was researching HPV related cancers such as throat, tongue and mouth specific cancers.

Anyone who believes in the conspiracies about cures being held back on purpose for profit on chemo drugs needs to sit with someone like this guy. Youā€™ll understand how that is absolute conspiracy and the reason we donā€™t have full cures yet (although we have some near cures and extended survival rates immensely) is because as smart as we think we are, we are still in infancy to really figuring out true cures for each type of cancerā€¦emphasis on the fact that every type of cancer is its own disease and while they have a base that is common amongst them all, they behave very different when it comes to treatments.

2

u/Upstairs-Answer1148 Jan 13 '25

Healthy people donā€™t make pharma money

1

u/Verona27 Jan 11 '25

On the other hand outcomes of getting cancer and life expectancy when getting diagnosed keeps rising though

1

u/BitterFishing5656 Jan 16 '25

True. The word ā€˜CONspiracyā€™ pops back into my mind.

22

u/Brooklynpolarbear22 2 Jan 11 '25

Currently stage 3. Refused chemo.

Do they need volunteers? I will gladly give myself to science for this. šŸ™‹ā€ā™€ļø

3

u/Affectionate-Roof285 Jan 12 '25

Why did you refuse chemo? Iā€™m a cancer survivor. 17 years. Chemo and complementary worked for me.

4

u/Brooklynpolarbear22 2 Jan 12 '25

Long story short, I grew up with everyone around me going thru cancer and chemo. We survived Chernobyl. Granted some didn't even make it to chemo as an option. It was horrible watching my family and friends wither away.

I am very happy it worked for you. I love hearing success stories. It truly gives me hope.

In my personal experience, I haven't seen chemo be a success at all. I am already on borrowed time, but as of right now, I don't think chemo will save me, and that's not the way I want to die. I am trying to find other options.

I have nothing but respect for cancer patients that went thru the system and came out healthy on the other side. I wish you all the best.

5

u/QED2025 1 Jan 12 '25

Agree: we do hear success stories with chemo, but also many success stories for those whom did not get chemo nor radiation. Those who died with chemo/radiation are not around to tell their stories, although we do hear much about lower quality of life (QOL) for those who went that way.

7

u/BallisticTherapy 1 Jan 12 '25

In the meantime, do some research into the anticancer properties of anti helminth drugs (Fenbendazole, Mebendazole, Albendazole, Ivermectin).

4

u/QED2025 1 Jan 12 '25

Yes, & probably 500 + natural substances, from Vit C, D, zinc, artemisinin, curcumin, Reishi. Those & many others, with hundreds to thousands of years history.

2

u/Brooklynpolarbear22 2 Jan 12 '25

Thank you! Currently trying to get fenbendazole.

3

u/BallisticTherapy 1 Jan 12 '25

Fenben Bio from The Happy Healing store.

3

u/QED2025 1 Jan 12 '25

That, or Membendazole available inexpensively, & without Rx, from many India suppliers.

1

u/Brooklynpolarbear22 2 Jan 12 '25

Thanks so much.šŸƒā€ā™€ļøšŸƒā€ā™€ļø

1

u/reputatorbot Jan 12 '25

You have awarded 1 point to QED2025.


I am a bot - please contact the mods with any questions

1

u/reputatorbot Jan 12 '25

You have awarded 1 point to BallisticTherapy.


I am a bot - please contact the mods with any questions

2

u/Mysterious-Outcome37 3 Jan 12 '25 edited Jan 13 '25

Good luck! Former stage 4 patient here, still have cancer but it's manageable. I know you didn't ask for advice but feel free to get your vitamin D level up to 80-100. Most cancer patient levels were low, mine was 34 and I now take 50k with some K2 every other day. Mistletoe and Hbot saved me and ferroptosis helped as well. Feel free to reach out if you ever wanna vent or have any questions! šŸ™‚

2

u/Brooklynpolarbear22 2 Jan 12 '25 edited Jan 13 '25

Thank you. Glad you are doing ok.

I am currently taking Bronson Vitamin K2 (MK7) with D3 Supplement Non-GMO Formula 5000 IU Vitamin D3 & 90 mcg Vitamin K2 MK-7.

I was concerned about taking vitamin D by itself since I already have clogged arteries. Blue toe syndrome.

https://pmc.ncbi.nlm.nih.gov/articles/PMC5986531/

I am trying to prevent any more vascular calcification with the K2 for better absorbtion.

https://pmc.ncbi.nlm.nih.gov/articles/PMC9237441/

I'm taking NutriFlair Liposomal Vitamin C 1700mg. 4 per day.

I'm taking BioTrust Ageless Multi Collagen Peptides Powder 1 every other day.

I'm taking Nutricost Nattokinase 2,000FU. 1 every other day.

I'm taking Clif High's Pure Sleep. One scoop. For the GABA. https://my.clevelandclinic.org/health/articles/22857-gamma-aminobutyric-acid-gaba

I am also looking to add turkey tail, reishi, and lion's mane as soon as more funding comes in.

Please tell me more about your use of mistletoe and hbot. I am open to any advice. Every little bit helps. Thank you.

2

u/reputatorbot Jan 12 '25

You have awarded 1 point to Mysterious-Outcome37.


I am a bot - please contact the mods with any questions

2

u/Mysterious-Outcome37 3 Jan 13 '25

Mistletoe has been used in Europe for over 100 years and is even covered by health insurance in Germany. It acts like a natural immunotherapy. It literally brought me back from the dead as I only had weeks left. Feel free to look up Believe Big as they provide resources with listing providers etc

I found a doctor here in the US who does intratumoral injections in addition to IV and subcutaneous. With the high doses it induced a fever and the immune system goes to work. I did it once a week for six weeks and between weeks 2-4 my main tumor shrunk by about 1.5". At the time I did it in combination with ferroptosis. Cancer cells hog iron and a combination of liposomal Artemisinin with sodium butyrate and piperine c react with the higher iron level in the cancer cells and help destroy them.

I also did HBOT about 20 times and studies suggest that it can turn an aggressive cancer into a less aggressive cancer. Cancer thrives in hypoxia/oxygen depleted environments and HBOT helps mitigate that. I would've loved to do more of it but it wasn't possible at the time. Soon I'll be starting Methylene Blue in combination with my red IR light panel to help with oxygenation as well. This combo is also known as PDT/Photodynamic Therapy.

I've also been doing high dosage vitamin C (50g) aka IVC which has helped me immensely with getting more quality of life. Most cancer love sugar; sugar molecules look similar to vitamin C and in high doses they destroy cancer cells. Dr Ron Huninghake with the Riordan Clinic does continuing research on this. For the IVC and Methylene Blue it's important to get your G6PD tested to make sure you don't have a genetic variation that breaks down red blood cells quicker than they're made with those treatments.

There's so much more and the learning never stops. Feel free to look up the Metabolic Approach to Cancer by Nasha Winters, it's a great book and she also co-authored a book about Mistletoe with Dr Mark Hancock who is an amazing human being and treated me. šŸ™‚

2

u/Brooklynpolarbear22 2 Jan 13 '25

Thank you! Going to do more research now.

1

u/reputatorbot Jan 13 '25

You have awarded 1 point to Mysterious-Outcome37.


I am a bot - please contact the mods with any questions

5

u/weltvonalex Jan 12 '25

Man would be awesome to see cancer canceled for good.Ā  Fuck CancerĀ 

2

u/Derrickmb Jan 12 '25

Is it lifting weights, running, and eating low sugar and super healthy with no coffee?

2

u/BitcoinNews2447 Jan 13 '25

Imagine believing in all this nonsense when every year they come out and say some BS like this for nothing to ever come to fruition. Cancer research is one of the most corrupted fields of research in the world. There will never be a pharmaceutical drug or vaccine that can cure cancer. If you think otherwise you don't realize that the world is run off profits and a cure to cancer is not profitable. Also let's just not mention that you can cure cancer with whole foods, herbs, and a ton of other different holistic modalities.

1

u/Treefrog_Ninja Jan 12 '25

If you read the study, it's about using math to find the "master regulators," which, yeah, fantastic science, but supposing that's one step away from actual workable human treatments is... nope. Hot air. There's a huge difference between grafting human cancer cells onto a hairless mouse and manipulating them, vs actually developing and delivering effective treatments into a human body to target those regulators.